This electronic document was downloaded from the GPO web site, November 2003, and is provided for information purposes only. The Code of Federal Regulations, Title 21, is updated April 1 of each year. The most current version of the regulations may be found at the GPO web site.
[Code of Federal Regulations]
[Title 21, Volume 3]
[Revised as of April 1, 2003]
From the U.S. Government Printing Office via GPO Access
[CITE: 21CFR177]
 
[Page 228-347]
 
                        TITLE 21--FOOD AND DRUGS
 
CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN 
                          SERVICES (CONTINUED)
 
PART 177--INDIRECT FOOD ADDITIVES: POLYMERS
 
Subpart A [Reserved]
 
Subpart B--Substances for Use as Basic Components of Single and Repeated 
                        Use Food Contact Surfaces
 
Sec.
177.1010  Acrylic and modified acrylic plastics, semirigid and rigid.
177.1020  Acrylonitrile/butadiene/styrene co-polymer.
177.1030  Acrylonitrile/butadiene/styrene/methyl methacrylate copolymer.
177.1040  Acrylonitrile/styrene copolymer.
177.1050  Acrylonitrile/styrene copolymer modified with butadiene/
          styrene elastomer.
177.1060  n-Alkylglutarimide/acrylic copolymers.
177.1200  Cellophane.
177.1210  Closures with sealing gaskets for food containers.
177.1211  Cross-linked polyacrylate copolymers.
177.1240  1,4-Cyclohexylene dimethylene terephthalate and 1,4-
          cyclohexylene dimethylene isophthalate copolymer.
177.1310  Ethylene-acrylic acid copolymers.
177.1312  Ethylene-carbon monoxide copolymers.
177.1315  Ethylene-1,4-cyclohexylene dimethylene terephthalate 
          copolymers.
177.1320  Ethylene-ethyl acrylate copolymers.
177.1330  Ionomeric resins.
177.1340  Ethylene-methyl acrylate copolymer resins.
177.1345  Ethylene/1,3-phenylene oxyethylene isophthalate/terephthalate 
          copolymer.
177.1350  Ethylene-vinyl acetate copolymers.
177.1360  Ethylene-vinyl acetate-vinyl alcohol copolymers.
177.1380  Fluorocarbon resins.
177.1390  Laminate structures for use at temperatures of 250  deg.F and 
          above.
177.1395  Laminate structures for use at temperatures between 120  deg.F 
          and 250 deg. F.
177.1400  Hydroxyethyl cellulose film, water-insoluble.
177.1420  Isobutylene polymers.
177.1430  Isobutylene-butene copolymers.
177.1440  4,4'-Isopropylidenediphenol-epichlorohydrin resins minimum 
          molecular weight 10,000.
177.1460  Melamine-formaldehyde resins in molded articles.
177.1480  Nitrile rubber modified acrylonitrile-methyl acrylate 
          copolymers.
177.1500  Nylon resins.
177.1520  Olefin polymers.
177.1550  Perfluorocarbon resins.
177.1555  Polyarylate resins.
177.1556  Polyaryletherketone resins.
177.1560  Polyarylsulfone resins.
177.1570  Poly-1-butene resins and butene/ethylene copolymers.
177.1580  Polycarbonate resins.
177.1585  Polyestercarbonate resins.
177.1590  Polyester elastomers.
177.1595  Polyetherimide resin.
177.1600  Polyethylene resins, carboxyl modified.
177.1610  Polyethylene, chlorinated.
177.1615  Polyethylene, fluorinated.
177.1620  Polyethylene, oxidized.
177.1630  Polyethylene phthalate polymers.
177.1632  Poly (phenyleneterephthalamide) resins.
177.1635  Poly(p-methylstyrene) and rubber-modified poly(p-
          methylstyrene).
177.1637  Poly(oxy-1,2-ethanediyloxycarbonyl-2,6-
          naphthalenediylcarbonyl) resins.
177.1640  Polystyrene and rubber-modified polystyrene.
177.1650  Polysulfide polymer-polyepoxy resins.
177.1655  Polysulfone resins.
 
[[Page 229]]
 
177.1660  Poly (tetramethylene terephthalate).
177.1670  Polyvinyl alcohol film.
177.1680  Polyurethane resins.
177.1810  Styrene block polymers.
177.1820  Styrene-maleic anhydride copolymers.
177.1830  Styrene-methyl methacrylate copolymers.
177.1850  Textryls.
177.1900  Urea-formaldehyde resins in molded articles.
177.1950  Vinyl chloride-ethylene copolymers.
177.1960  Vinyl chloride-hexene-1 copolymers.
177.1970  Vinyl chloride-lauryl vinyl ether copolymers.
177.1980  Vinyl chloride-propylene copolymers.
177.1990  Vinylidene chloride/methyl acrylate copolymers.
177.2000  Vinylidene chloride/methyl acrylate/methyl methacrylate 
          polymers.
 
 Subpart C--Substances for Use Only as Components of Articles Intended 
                            for Repeated Use
 
177.2210  Ethylene polymer, chlorosulfonated.
177.2250  Filters, microporous polymeric.
177.2260  Filters, resin-bonded.
177.2280  4,4'-Isopropylidenediphenol-epichlorohydrin thermosetting 
          epoxy resins.
177.2355  Mineral reinforced nylon resins.
177.2400  Perfluorocarbon cured elastomers.
177.2410  Phenolic resins in molded articles.
177.2415  Poly(aryletherketone) resins.
177.2420  Polyester resins, cross-linked.
177.2430  Polyether resins, chlorinated.
177.2440  Polyethersulfone resins.
177.2450  Polyamide-imide resins.
177.2460  Poly(2,6-dimethyl-1,4-phenylene) oxide resins.
177.2465  Polymethylmethacrylate/poly(tri methoxysilylpropyl) 
          methacrylate copolymers.
177.2470  Polyoxymethylene copolymer.
177.2480  Polyoxymethylene homopolymer.
177.2490  Polyphenylene sulfide resins.
177.2500  Polyphenylene sulfone resins.
177.2510  Polyvinylidene fluoride resins.
177.2550  Reverse osmosis membranes.
177.2600  Rubber articles intended for repeated use.
177.2710  Styrene-divinylbenzene resins, cross-linked.
177.2800  Textiles and textile fibers.
177.2910  Ultra-filtration membranes.
 
    Authority: 21 U.S.C. 321, 342, 348, 379e.
 
    Source: 42 FR 14572, Mar. 15, 1977, unless otherwise noted.
 
    Editorial Note: Nomenclature changes to part 177 appear at 61 FR 
14482, Apr. 2, 1996, 66 FR 56035, Nov. 6, 2001, 66 FR 66742, Dec. 27, 
2001, and 68 FR 15355, Mar. 31, 2003.
 
 
 
 
[Code of Federal Regulations]
[Title 21, Volume 3]
[Revised as of April 1, 2003]
From the U.S. Government Printing Office via GPO Access
[CITE: 21CFR177.1010]
 
[Page 229-234]
 
                        TITLE 21--FOOD AND DRUGS
 
CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN 
                          SERVICES (CONTINUED)
 
PART 177--INDIRECT FOOD ADDITIVES: POLYMERS--Table of Contents
 
Subpart B--Substances for Use as Basic Components of Single and Repeated 
                        Use Food Contact Surfaces
 
Sec. 177.1010  Acrylic and modified acrylic plastics, semirigid and rigid.
 
 
    Semirigid and rigid acrylic and modified acrylic plastics may be 
safely used as articles intended for use in contact with food, in 
accordance with the following prescribed conditions. The acrylic and 
modified acrylic polymers or plastics described in this section also may 
be safely used as components of articles intended for use in contact 
with food.
    (a) The optional substances that may be used in the formulation of 
the semirigid and rigid acrylic and modified acrylic plastics, or in the 
formulation of acrylic and modified acrylic components of articles, 
include substances generally recognized as safe in food, substances used 
in accordance with a prior sanction or approval, substances permitted 
for use in such plastics by regulations in parts 170 through 189 of this 
chapter, and substances identified in this paragraph. At least 50 
weight-percent of the polymer content of the acrylic and modified 
acrylic materials used as finished articles or as components of articles 
shall consist of polymer units derived from one or more of the acrylic 
or methacrylic monomers listed in paragraph (a)(1) of this section.
    (1) Homopolymers and copolymers of the following monomers:
 
n-Butyl acrylate.
n-Butyl methacrylate.
Ethyl acrylate.
2-Ethylhexyl acrylate.
Ethyl methacrylate.
Methyl acrylate.
Methyl methacrylate.
 
    (2) Copolymers produced by copolymerizing one or more of the 
monomers listed in paragraph (a)(1) of this section with one or more of 
the following monomers:
 
Acrylonitrile.
 
[[Page 230]]
 
Methacrylonitrile.
[alpha]-Methylstyrene.
Styrene.
Vinyl chloride.
Vinylidene chloride.
 
    (3) Polymers identified in paragraphs (a)(1) and (2) of this section 
containing no more than 5 weight-percent of total polymer units derived 
by copolymerization with one or more of the monomers listed in paragraph 
(a)(3)(i) and (ii) of this section. Monomers listed in paragraph 
(a)(3)(ii) of this section are limited to use only in plastic articles 
intended for repeated use in contact with food.
    (i) List of minor monomers:
 
Acrylamide.
Acrylic acid
1,3-Butylene glycol dimethacrylate.
1,4-Butylene glycol dimethacrylate.
Diethylene glycol dimethacrylate.
Diproplylene glycol dimethacrylate.
Divinylbenzene.
Ethylene glycol dimethacrylate.
Itaconic acid.
Methacrylic acid.
N-Methylolacrylamide.
N-Methylolmethacrylamide.
4-Methyl-1,4-pentanediol dimethacrylate.
Propylene glycol dimethacrylate.
Trivinylbenzene.
 
    (ii) List of minor monomers limited to use only in plastic articles 
intended for repeated use in contact with food:
 
Allyl methacrylate [Chemical Abstracts Service Registry No. 96-05-9]
tert-Butyl acrylate.
tert-Butylaminoethyl methacrylate.
sec-Butyl methacrylate.
tert-Butyl methacrylate.
Cyclohexyl methacrylate.
Dimethylaminoethyl methacrylate.
2-Ethylhexyl methacrylate.
Hydroxyethyl methacrylate.
Hydroxyethyl vinyl sulfide.
Hydroxypropyl methacrylate.
Isobornyl methacrylate.
Isobutyl methacrylate.
Isopropyl acrylate.
Isopropyl methacrylate.
Methacrylamide.
Methacrylamidoethylene urea.
Methacryloxyacetamidoethylethylene urea.
Methacryloxyacetic acid.
n-Propyl methacrylate.
3,5,5-Trimethylcyclohexyl methacrylate.
 
    (4) Polymers identified in paragraphs (a)(1), (2), and (3) of this 
section are mixed together and/or with the following polymers, provided 
that no chemical reactions, other than addition reactions, occur when 
they are mixed:
 
Butadiene-acrylonitrile copolymers.
Butadiene-acrylonitrile-styrene copolymers.
Butadiene-acrylonitrile-styrene-methyl methacrylic copolymers.
Butadiene-styrene copolymers.
Butyl rubber.
Natural rubber.
Polybutadiene.
Poly (3-chloro-1,3-butadiene).
Polyester identified in Sec. 175.300(b)(3)(vii) of this chapter.
Polyvinyl chloride.
Vinyl chloride copolymers complying with Sec. 177.1980.
Vinyl chloride-vinyl acetate copolymers.
 
    (5) Antioxidants and stabilizers identified in 
Sec. 175.300(b)(3)(xxx) of this chapter and the following:
 
Di-tert-butyl-p-cresol.
2-Hydroxy-4-methoxybenzophenone.
2-Hydroxy-4-methoxy-2-carboxybenzophenone.
3-Hydroxyphenyl benzoate.
p-Methoxyphenol.
Methyl salicylate.
Octadecyl 3,5-di-tert-butyl-4-hydroxyhydrocinnamate (CAS Reg. No. 2082-
79-3): For use only: (1) At levels not exceeding 0.2 percent by weight 
in semirigid and rigid acrylic and modified acrylic plastics, where the 
finished articles contact foods containing not more than 15 percent 
alcohol; and (2) at levels not exceeding 0.01 percent by weight in 
semirigid and rigid acrylic and modified acrylic plastics intended for 
repeated food-contact use where the finished article may be used for 
foods containing more than 15 percent alcohol.
Phenyl salicylate.
 
    (6) Release agents: Fatty acids derived from animal and vegetable 
fats and oils, and fatty alcohols derived from such acids.
    (7) Surface active agent: Sodium dodecylbenzenesulfonate.
    (8) Miscellaneous materials:
 
Di(2-ethylhexyl) phthalate, for use only as a flow promoter at a level 
not to exceed 3 weight-percent based on the monomers.
Dimethyl phthalate.
Oxalic acid, for use only as a polymerization catalyst aid.
Tetraethylenepentamine, for use only as a catalyst activator at a level 
not to exceed 0.5 weight-percent based on the monomers.
Toluene.
Xylene.
 
    (b) The semirigid and rigid acrylic and modified acrylic plastics, 
in the
 
[[Page 231]]
 
finished form in which they are to contact food, when extracted with the 
solvent or solvents characterizing the type of food and under the 
conditions of time and temperature as determined from tables 1 and 2 of 
Sec. 176.170(c) of this chapter, shall yield extractives not to exceed 
the following, when tested by the methods prescribed in paragraph (c) of 
this section. The acrylic and modified acrylic polymers or plastics 
intended to be used as components of articles also shall yield 
extractives not to exceed the following limitations when prepared as 
strips as described in paragraph (c)(2) of this section:
    (1) Total nonvolatile extractives not to exceed 0.3 milligram per 
square inch of surface tested.
    (2) Potassium permanganate oxidizable distilled water and 8 and 50 
percent alcohol extractives not to exceed an absorbance of 0.15.
    (3) Ultraviolet-absorbing distilled water and 8 and 50 percent 
alcohol extractives not to exceed an absorbance of 0.30.
    (4) Ultraviolet-absorbing n-heptane extractives not to exceed an 
absorbance of 0.10.
    (c) Analytical methods--(1) Selection of extractability conditions. 
These are to be chosen as provided in Sec. 176.170(c) of this chapter.
    (2) Preparation of samples. Sufficient samples to allow duplicates 
of all applicable tests shall be cut from the articles or formed from 
the plastic composition under tests, as strips about 2.5 inches by about 
0.85-inch wide by about 0.125-inch thick. The total exposed surface 
should be 5 square inches 0.5-square inch. The samples, 
after preparation, shall be washed with a clean brush under hot 
tapwater, rinsed under running hot tapwater (140  deg.F minimum), rinsed 
with distilled water, and air-dried in a dust-free area or in a 
desiccator.
    (3) Preparation of solvents. The water used shall be double-
distilled water, prepared in a still using a block tin condenser. The 8 
and 50 percent (by volume) alcohol solvents shall be prepared from ethyl 
alcohol meeting the specifications of the United States Pharmacopeia XX 
and diluted with double-distilled water that has been prepared in a 
still using a tin block condenser. The n-heptane shall be 
spectrophotometric grade. Adequate precautions must be taken to keep all 
solvents dust-free.
    (4) Blank values on solvents. (i) Duplicate determinations of 
residual solids shall be run on samples of each solvent that have been 
exposed to the temperature-time conditions of the extraction test 
without the plastic sample. Sixty milliliters of exposed solvent is 
pipetted into a clean, weighed platinum dish, evaporated to 2-5 
milliliters on a nonsparking, low-temperature hot plate and dried in 212 
 deg.F oven for 30 minutes. The residue for each solvent shall be 
determined by weight and the average residue weight used as the blank 
value in the total solids determination set out in paragraph (c)(6) of 
this section. The residue for an acceptable solvent sample shall not 
exceed 0.5 milligram per 60 milliliters.
    (ii) For acceptability in the ultraviolet absorbers test, a sample 
of each solvent shall be scanned in an ultraviolet spectrophotometer in 
5-centimeter silica spectrophotometric absorption cells. The absorbance 
of the distilled water when measured versus air in the reference cell 
shall not exceed 0.03 at any point in the wavelength region of 245 to 
310 m[mu]. The absorbance of the 8 percent alcohol when measured versus 
distilled water in the reference cell shall not exceed 0.01 at any point 
in the wavelength region of 245 to 310 m[mu]. The absorbance of the 50 
percent alcohol when measured versus distilled water in the reference 
cell shall not exceed 0.05 at any point in the wavelength region of 245 
to 310 m[mu]. The absorbance of the heptane when measured versus 
distilled water in the reference cell shall not exceed 0.15 at 245, 0.09 
at 260, 0.04 at 270, and 0.02 at any point in the wavelength region of 
280 to 310 m[mu].
    (iii) Duplicate ultraviolet blank determinations shall be run on 
samples of each solvent that has been exposed to the temperature-time 
conditions of the extraction test without the plastic sample. An aliquot 
of the exposed solvent shall be measured versus the unexposed solvent in 
the reference cell. The average difference in the absorbances at any 
wavelength in the region of 245 to 310 m[mu] shall be used as a blank 
correction for the ultraviolet
 
[[Page 232]]
 
absorbers measured at the same wavelength according to paragraph 
(c)(8)(ii) of this section.
    (iv) The acceptability of the solvents for use in the permanganate 
test shall be determined by preparing duplicate permanganate test blanks 
according to paragraph (c)(7)(iv) of this section. For this test, the 
directions referring to the sample extract shall be disregarded. The 
blanks shall be scanned in 5-centimeter silica spectrophotometric cells 
in the spectrophotometer versus the appropriate solvent as reference. 
The absorbance in distilled water in the wavelength region of 544 to 552 
m[mu] should be 1.16 but must not be less than 1.05 nor more than 1.25. 
The absorbance in the 8 and 50 percent alcohol must not be less than 
0.85 nor more than 1.15.
    (v) Duplicate permanganate test determinations shall be run on 
samples of distilled water and 8 and 50 percent alcohol solvents that 
have been exposed to the temperature-time conditions of the extraction 
test without the plastic sample. The procedure shall be as described in 
paragraph (c)(7)(iv) of this section, except that the appropriate 
exposed solvent shall be substituted where the directions call for 
sample extract. The average difference in the absorbances in the region 
of 544 to 552 m[mu] shall be used as a blank correction for the 
determination of permanganate oxidizable extractives according to 
paragraph (c)(7)(iv) of this section.
    (5) Extraction procedure. For each extraction, place a plastic 
sample in a clean 25 millimeters x 200 millimeters hard-glass test tube 
and add solvent equal to 10 milliliters of solvent per square inch of 
plastic surface. This amount will be between 45 milliliters and 55 
milliliters. The solvent must be preequilibrated to the temperature of 
the extraction test. Close the test tube with a ground-glass stopper and 
expose to the specified temperature for the specified time. Cool the 
tube and contents to room temperature if necessary.
    (6) Determination of total nonvolatile extractives. Remove the 
plastic strip from the solvent with a pair of clean forceps and wash the 
strip with 5 milliliters of the appropriate solvent, adding the washings 
to the contents of the test tube. Pour the contents of the test tube 
into a clean, weighed platinum dish. Wash the tube with 5 milliliters of 
the appropriate solvent and add the solvent to the platinum dish. 
Evaporate the solvent to 2-5 milliliters on a nonsparking, low-
temperature hotplate. Complete the evaporation in a 212  deg.F oven for 
30 minutes. Cool the dish in a desiccator for 30 minutes and weigh to 
the nearest 0.1 milligram. Calculate the total nonvolatile extractives 
as follows:
[GRAPHIC] [TIFF OMITTED] TR01JA93.392
 
[GRAPHIC] [TIFF OMITTED] TR01JA93.393
 
where:
 
e=Total increase in weight of the dish, in milligrams.
b=Blank value of the solvent in milligrams, as determined in paragraph 
(c)(4)(i) of this section.
s=Total surface of the plastic sample in square inches.
 
    (7) Determination of potassium permanganate oxidizable extractives. 
(i) Pipette 25 milliliters of distilled water into a clean 125-
milliliter Erlenmeyer flask that has been rinsed several times with 
aliquots of distilled water. This is the blank. Prepare a distilled 
water solution containing 1.0 part per million of p-methoxyphenol 
(melting point 54-56  deg.C, Eastman grade or equivalent). Pipette 25 
milliliters of this p-methoxyphenol solution into a rinsed Erlenmeyer 
flask. Pipette exactly 3.0 milliliters of 154 parts per million aqueous 
potassium permanganate solution into the p-methoxyphenol and exactly 3.0 
milliliters into the blank, in that order. Swirl both flasks to mix the 
contents and then transfer aliquots from each flask into matched 5-
centimeter spectrophotometric absorption cells. The cells are placed in 
the spectrophotometer cell compartment with the p-methoxyphenol solution 
in the reference beam. Spectrophotometric measurement is conducted as in 
paragraph (c)(7)(iv) of this section. The absorbance reading in the 
region 544-552 m[mu] should be 0.24 but must be not less than 0.12 nor 
more than 0.36. This test
 
[[Page 233]]
 
shall be run in duplicate. For the purpose of ascertaining compliance 
with the limitations in paragraph (b)(2) of this section, the absorbance 
measurements obtained on the distilled water extracts according to 
paragraph (c)(7)(iv) of this section shall be multiplied by a correction 
factor, calculated as follows:
[GRAPHIC] [TIFF OMITTED] TR01JA93.394
 
    (ii) The procedure in paragraph (c)(7)(i) of this section is 
repeated except that, in this instance, the solvent shall be 8 percent 
alcohol. The absorbance in the region 544-552 m[mu] should be 0.26 but 
must be not less than 0.13 nor more than 0.39. This test shall be run in 
duplicate. For the purpose of ascertaining compliance with the 
limitations prescribed in paragraph (b)(2) of this section, the 
absorbance measurements obtained on the 8 percent alcohol extracts 
according to paragraph (c)(7)(iv) of this section shall be multiplied by 
a correction factor, calculated as follows:
[GRAPHIC] [TIFF OMITTED] TR01JA93.395
 
    (iii) The procedure in paragraph (c)(7)(i) of this section is 
repeated except that, in this instance, the solvent shall be 50 percent 
alcohol. The absorbance in the region 544-552 m[mu] should be 0.25 but 
must be not less than 0.12 nor more than 0.38. This test shall be run in 
duplicate. For the purpose of ascertaining compliance with the 
limitations prescribed in paragraph (b)(2) of this section, the 
absorbance measurements obtained on the 50 percent alcohol extracts 
according to paragraph (c)(7)(iv) of this section shall be multiplied by 
a correction factor, calculated as follows:
[GRAPHIC] [TIFF OMITTED] TR01JA93.396
 
    (iv) Water and 8 and 50 percent alcohol extracts. Pipette 25 
milliliters of the appropriate solvent into a clean, 125-milliliter 
Erlenmeyer flask that has been rinsed several times with aliquots of the 
same solvent. This is the blank. Into another similarly rinsed flask, 
pipette 25 milliliters of the sample extract that has been exposed under 
the conditions specified in paragraph (c)(5) of this section. Pipette 
exactly 3.0 milliliters of 154 parts per million aqueous potassium 
permanganate solution into the sample and exactly 3.0 milliliters into 
the blank, in that order. Before
 
[[Page 234]]
 
use, the potassium permanganate solution shall be checked as in 
paragraph (c)(7)(i) of this section. Both flasks are swirled to mix the 
contents, and then aliquots from each flask are transferred to matched 
5-centimeter spectrophotometric absorption cells. Both cells are placed 
in the spectrophotometer cell compartment with the sample solution in 
the reference beam. The spectrophotometer is adjusted for 0 and 100 
percent transmittance at 700 m[mu]. The spectrum is scanned on the 
absorbance scale from 700 m[mu] to 500 m[mu] in such a way that the 
region 544 m[mu] to 552 m[mu] is scanned within 5 minutes to 10 minutes 
of the time that permanganate was added to the solutions. The height of 
the absorbance peak shall be measured, corrected for the blank as 
determined in paragraph (c)(4)(v) of this section, and multiplied by the 
appropriate correction factor determined according to paragraph (c)(7) 
(i), (ii), and (iii) of this section. This test shall be run in 
duplicate and the two results averaged.
    (8) Determination of ultraviolet-absorbing extractives. (i) A 
distilled water solution containing 1.0 part per million of p-
methoxyphenol (melting point 54  deg.C-56  deg.C. Eastman grade or 
equivalent) shall be scanned in the region 360 to 220 m[mu] in 5-
centimeter silica spectrophotometric absorption cells versus a distilled 
water reference. The absorbance at the wavelength of maximum absorbance 
(should be about 285 m[mu]) is about 0.11 but must be not less than 0.08 
nor more than 0.14. This test shall be run in duplicate. For the purpose 
of ascertaining compliance with the limitations prescribed in paragraph 
(b) (3) and (4) of this section, the absorbance obtained on the extracts 
according to paragraph (c)(8)(ii) of this section shall be multiplied by 
a correction factor, calculated as follows:
[GRAPHIC] [TIFF OMITTED] TR01JA93.397
 
    (ii) An aliquot of the extract that has been exposed under the 
conditions specified in paragraph (c)(5) of this section is scanned in 
the wavelength region 360 to 220 m[mu] versus the appropriate solvent 
reference in matched 5-centimeter silica spectrophotometric absorption 
cells. The height of any absorption peak shall be measured, corrected 
for the blank as determined in paragraph (c)(4)(iii) of this section, 
and multiplied by the correction factor determined according to 
paragraph (c)(8)(i) of this section.
    (d) In accordance with current good manufacturing practice, finished 
semirigid and rigid acrylic and modified acrylic plastics, and articles 
containing these polymers, intended for repeated use in contact with 
food shall be thoroughly cleansed prior to their first use in contact 
with food.
    (e) Acrylonitrile copolymers identified in this section shall comply 
with the provisions of Sec. 180.22 of this chapter.
    (f) The acrylic and modified acrylic polymers identified in and 
complying with this section, when used as components of the food-contact 
surface of an article that is the subject of a regulation in this part 
and in parts 174, 175, 176, and 178 of this chapter, shall comply with 
any specifications and limitations prescribed by such regulation for the 
article in the finished form in which it is to contact food.
 
[42 FR 14572, Mar. 15, 1977; 42 FR 56728, Oct. 28, 1977, as amended at 
43 FR 54927, Nov. 24, 1978; 45 FR 67320, Oct. 10, 1980; 46 FR 46796, 
Sept. 22, 1981; 49 FR 10108, Mar. 19, 1984; 49 FR 13139, Apr. 3, 1984; 
50 FR 31045, July 24, 1985]
 
 
 
 
 
[Code of Federal Regulations]
[Title 21, Volume 3]
[Revised as of April 1, 2003]
From the U.S. Government Printing Office via GPO Access
[CITE: 21CFR177.1020]
 
[Page 234-235]
 
                        TITLE 21--FOOD AND DRUGS
 
CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN 
                          SERVICES (CONTINUED)
 
PART 177--INDIRECT FOOD ADDITIVES: POLYMERS--Table of Contents
 
Subpart B--Substances for Use as Basic Components of Single and Repeated 
                        Use Food Contact Surfaces
 
Sec. 177.1020  Acrylonitrile/butadiene/styrene co-polymer.
 
    Acrylonitrile/butadiene/styrene copolymer identified in this section 
may be safely used as an article or component of articles intended for 
use with
 
[[Page 235]]
 
all foods, except those containing alcohol, under conditions of use E, 
F, and G described in table 2 of Sec. 176.170(c) of this chapter.
    (a) Identity. For the purpose of this section, the acrylonitrile/
butadiene/styrene copolymer consists of:
    (1) Eighty-four to eighty-nine parts by weight of a matrix polymer 
containing 73 to 78 parts by weight of acrylonitrile and 22 to 27 parts 
by weight of styrene; and
    (2) Eleven to sixteen parts by weight of a grafted rubber consisting 
of (i) 8 to 13 parts of butadiene/styrene elastomer containing 72 to 77 
parts by weight of butadiene and 23 to 28 parts by weight of styrene and 
(ii) 3 to 8 parts by weight of a graft polymer having the same 
composition range as the matrix polymer.
    (b) Adjuvants. The copolymer identified in paragraph (a) of this 
section may contain adjuvant substances required in its production. Such 
adjuvants may include substances generally recognized as safe in food, 
substances used in accordance with prior sanction, substances permitted 
in this part, and the following:
 
------------------------------------------------------------------------
                 Substance                           Limitations
------------------------------------------------------------------------
2-Mercapto- ethanol.......................  The finished copolymer shall
                                             contain not more than 100
                                             ppm 2-mercaptoethanol
                                             acrylonitrile adduct as
                                             determined by a method
                                             titled "Analysis of
                                             Cycopac Resin for Residual
                                             [beta]-(2-
                                             Hydroxyethylmercapto)
                                             propionitrile," which is
                                             incorporated by reference.
                                             Copies are available from
                                             the Bureau of Foods (HFS-
                                             200), Food and Drug
                                             Administration, 5100 Paint
                                             Branch Pkwy., College Park,
                                             MD 20740, or available for
                                             inspection at the Office of
                                             the Federal Register, 800
                                             North Capitol Street, NW.,
                                             suite 700, Washington, DC
                                             20408.
------------------------------------------------------------------------
 
    (c) Specifications. (1) Nitrogen content of the copolymer is in the 
range of 16 to 18.5 percent as determined by Micro-Kjeldahl analysis.
    (2) Residual acrylonitrile monomer content of the finished copolymer 
articles is not more than 11 parts per million as determined by a gas 
chromatographic method titled "Determination of Residual Acrylonitrile 
and Styrene Monomers-Gas Chromatographic Internal Standard Method," 
which is incorporated by reference. Copies are available from the Center 
for Food Safety and Applied Nutrition (HFS-200), Food and Drug 
Administration, 5100 Paint Branch Pkwy., College Park, MD 20740, or 
available for inspection at the Office of the Federal Register, 800 
North Capitol Street, NW., suite 700, Washington, DC 20408.
    (d) Extractive limitations. (1) Total nonvolatile extractives not to 
exceed 0.0005 milligram per square inch surface area when the finished 
food contact article is exposed to distilled water, 3 percent acetic 
acid, or n-heptane for 8 days at 120  deg.F.
    (2) The finished food-contact article shall yield not more than 
0.0015 milligram per square inch of acrylonitrile monomer when exposed 
to distilled water and 3 percent acetic acid at 150  deg.F for 15 days 
when analyzed by a polarographic method titled "Extracted Acrylonitrile 
by Differential Pulse Polarography," which is incorporated by 
reference. Copies are available from the Center for Food Safety and 
Applied Nutrition (HFS-200), Food and Drug Administration, 5100 Paint 
Branch Pkwy., College Park, MD 20740, or available for inspection at the 
Office of the Federal Register, 800 North Capitol Street, NW., suite 
700, Washington, DC 20408.
    (e) Acrylonitrile copolymers identified in this section shall comply 
with the provisions of Sec. 180.22 of this chapter.
    (f) Acrylonitrile copolymers identified in this section are not 
authorized to be used to fabricate beverage containers.
 
[42 FR 14572, Mar. 15, 1977, as amended at 42 FR 48543, Sept. 23, 1977; 
47 FR 11841, Mar. 19, 1982; 54 FR 24897, June 12, 1989]
 
 
 
 
 
[Code of Federal Regulations]
[Title 21, Volume 3]
[Revised as of April 1, 2003]
From the U.S. Government Printing Office via GPO Access
[CITE: 21CFR177.1030]
 
[Page 235-236]
 
                        TITLE 21--FOOD AND DRUGS
 
CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN 
                          SERVICES (CONTINUED)
 
PART 177--INDIRECT FOOD ADDITIVES: POLYMERS--Table of Contents
 
Subpart B--Substances for Use as Basic Components of Single and Repeated 
                        Use Food Contact Surfaces
 
Sec. 177.1030  Acrylonitrile/butadiene/styrene/methyl methacrylate copolymer.
 
    Acrylonitrile/butadiene/styrene/methyl methacrylate copolymer 
identified in this section may be safely used as an article or component 
of articles intended for use with food identified in table 1 of 
Sec. 176.170(c) of this chapter as Type I, II, III, IVA, IVB, V,
 
[[Page 236]]
 
VIB, (except bottles intended to hold carbonated beverages), VIIA, VIIB, 
VIII and IX, under conditions of use C, D, E, F, and G described in 
table 2 of Sec. 176.170(c) of this chapter with a high temperature 
limitation of 190  deg.F.
    (a) Identity. For the purpose of this section, acrylonitrile/
butadiene/styrene/methyl methacrylate copolymer consists of: (1) 73 to 
79 parts by weight of a matrix polymer containing 64 to 69 parts by 
weight of acrylonitrile, 25 to 30 parts by weight of styrene and 4 to 6 
parts by weight of methyl methacrylate; and (2) 21 to 27 parts by weight 
of a grafted rubber consisting of (i) 16 to 20 parts of butadiene/
styrene/elastomer containing 72 to 77 parts by weight of butadiene and 
23 to 28 parts by weight of styrene and (ii) 5 to 10 parts by weight of 
a graft polymer having the same composition range as the matrix polymer.
    (b) Adjuvants. The copolymer identified in paragraph (a) of this 
section may contain adjuvant substances required in its production. Such 
adjuvants may include substances generally recognized as safe in food, 
substances used in accordance with prior sanction, substances permitted 
under applicable regulations in this part, and the following:
 
------------------------------------------------------------------------
                Substances                           Limitations
------------------------------------------------------------------------
2-Mercaptoethanol.........................  The finished copolymer shall
                                             contain not more than 800
                                             ppm 2-mercaptoethanol
                                             acrylonitrile adduct as
                                             determined by a method
                                             titled "Analysis of
                                             Cycopac Resin for Residual
                                             [beta]-(2-
                                             Hydroxyethylmercapto)
                                             propionitrile," which is
                                             incorporated by reference.
                                             Copies are available from
                                             the Bureau of Foods (HFS-
                                             200), Food and Drug
                                             Administration, 5100 Paint
                                             Branch Pkwy., College Park,
                                             MD 20740, or available for
                                             inspection at the Office of
                                             the Federal Register, 800
                                             North Capitol Street, NW.,
                                             suite 700, Washington, DC
                                             20408.
------------------------------------------------------------------------
 
    (c) Specifications. (1) Nitrogen content of the copolymer is in the 
range of 13.0 to 16.0 percent as determined by Micro-Kjeldahl analysis.
    (2) Residual acrylonitrile monomer content of the finished copolymer 
articles is not more than 11 parts per million as determined by a gas 
chromatographic method titled "Determination of Residual Acrylonitrile 
and Styrene Monomers-Gas Chromatographic Internal Standard Method," 
which is incorporated by reference. Copies are available from the Center 
for Food Safety and Applied Nutrition (HFS-200), Food and Drug 
Administration, 5100 Paint Branch Pkwy., College Park, MD 20740, or 
available for inspection at the Office of the Federal Register, 800 
North Capitol Street, NW., suite 700, Washington, DC 20408.
    (d) Extractive limitations. (1) Total nonvolatile extractives not to 
exceed 0.0005 milligram per square inch surface area of the food-contact 
article when exposed to distilled water, 3 percent acetic acid, 50 
percent ethanol, and n-heptane for 10 days at 120  deg.F.
    (2) The finished food-contact article shall yield not more than 
0.0025 milligram per square inch of acrylonitrile monomer when exposed 
to distilled water, 3 percent acetic acid and n-heptane at 190  deg.F 
for 2 hours, cooled to 120  deg.F (80 to 90 minutes) and maintained at 
120  deg.F for 10 days when analyzed by a polarographic method titled 
"Extracted Acrylonitrile by Differential Pulse Polarography," which is 
incorporated by reference. Copies are available from the Center for Food 
Safety and Applied Nutrition (HFS-200), Food and Drug Administration, 
5100 Paint Branch Pkwy., College Park, MD 20740, or available for 
inspection at the Office of the Federal Register, 800 North Capitol 
Street, NW., suite 700, Washington, DC 20408.
    (e) Acrylonitrile copolymers identified in this section shall comply 
with the provisions of Sec. 180.22 of this chapter.
    (f) Acrylonitrile copolymers identified in this section are not 
authorized to be used to fabricate beverage containers.
 
[42 FR 14572, Mar. 15, 1977, as amended at 42 FR 48543, Sept. 23, 1977; 
47 FR 11841, Mar. 19, 1982; 54 FR 24898, June 12, 1989]
 
 
 
 
 
[Code of Federal Regulations]
[Title 21, Volume 3]
[Revised as of April 1, 2003]
From the U.S. Government Printing Office via GPO Access
[CITE: 21CFR177.1040]
 
[Page 236-238]
 
                        TITLE 21--FOOD AND DRUGS
 
CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN 
                          SERVICES (CONTINUED)
 
PART 177--INDIRECT FOOD ADDITIVES: POLYMERS--Table of Contents
 
Subpart B--Substances for Use as Basic Components of Single and Repeated 
                        Use Food Contact Surfaces
 
Sec. 177.1040  Acrylonitrile/styrene copoly-mer.
 
    Acrylonitrile/styrene copolymers identified in this section may be 
safely
 
[[Page 237]]
 
used as a component of packaging materials subject to the provisions of 
this section.
    (a) Identity. For the purposes of this section acrylonitrile/styrene 
copoly-mers are basic copolymers meeting the specifications prescribed 
in paragraph (c) of this section.
    (b) Adjuvants. (1) The copolymers identified in paragraph (c) of 
this section may contain adjuvant substances required in their 
production, with the exception that they shall not contain mercaptans or 
other substances which form reversible complexes with acryl-onitrile 
monomer. Permissible adjuvants may include substances generally 
recognized as safe in food, substances used in accordance with prior 
sanction, substances permitted under applicable regulations in this 
part, and those authorized in paragraph (b)(2) of this section.
    (2) The optional adjuvants for the acrylonitrile/styrene copolymer 
identified in paragraphs (c) (1) and (3) of this section are as follows:
 
------------------------------------------------------------------------
                Substances                           Limitation
------------------------------------------------------------------------
Condensation polymer of toluene             0.15 pct maximum.
 sulfonamide and formaldehyde.
------------------------------------------------------------------------
 
    (c) Specifications.
 
----------------------------------------------------------------------------------------------------------------
                                                                           Maximum
                                  Maximum residual                       extractable
                                    acrylonitrile       Nitrogen        fractions at         Conformance with
Acrylonitrile/styrene copolymers   monomer content     content of         specified       certain specifications
                                     of finished       copolymer      temperatures and
                                       article                              times
----------------------------------------------------------------------------------------------------------------
1. Acrylonitrile/styrene          80 ppm\1\.......  17.4 to 19 pct.  Total nonvolatile   Minimum number average
 copolymer consisting of the                                          extractives not     molecular weight is
 copolymer produced by                                                to exceed 0.01 mg/  30,000.\1\
 polymerization of 66-72 parts                                        in \2\ surface
 by weight of acrylonitrile and                                       area of the food
 28-34 parts by weight of                                             contact article
 styrene; for use with food of                                        when exposed to
 Type VI-B identified in table 1                                      distilled water
 of Sec.  176.170(c) of this                                          and 3 pct acetic
 chapter under conditions of use                                      acid for 10 d at
 C, D, E, F, G described in                                           66  deg.C (150
 table 2 of Sec.  176.170(c) of                                       deg.F).
 this chapter.                                                       The extracted
                                                                      copolymer shall
                                                                      not exceed 0.001
                                                                      mg/in \2\ surface
                                                                      area of the food
                                                                      contact article
                                                                      when exposed to
                                                                      distilled water
                                                                      and 3 pct acetic
                                                                      acid for 10 d at
                                                                      66  deg.C (150
                                                                      deg.F) \1\.
2. Acrylonitrile/styrene          50 ppm\1\.......  12.2 to 17.2     Extracted           Minimum 10 pct solution
 copolymer consisting of the                         pct.             copolymer not to    viscosity at 25  deg.C
 copolymer produced by                                                exceed 2.0 ppm in   (77  deg.F) is
 polymerization of 45-65 parts                                        aqueous extract     10cP.\1\
 by weight of acrylonitrile and                                       or n-heptane
 35-55 parts by weigth of                                             extract obtained
 styrene; for use with food of                                        when 100 g sample
 Types, I, II, III, IV, V, VI                                         of the basic
 (except bottles), VII, VIII,                                         copolymer in the
 and IX identified in table 1 of                                      form of particles
 Sec.  176.170(c) of this                                             of a size that
 chapter under conditions B (not                                      will pass through
 to exceed 93  deg.C (200                                             a U.S. Standard
 deg.F)), C, D, E, F, G                                               Sieve No. 6 and
 described in table 2 of Sec.                                         that will be held
 176.170(c) of this chapter.                                          on a U.S.
                                                                      Standard Sieve
                                                                      No. 10 is
                                                                      extracted with
                                                                      250 mil of
                                                                      deionized water
                                                                      or reagent grade
                                                                      n-heptane at
                                                                      reflux
                                                                      temperature for 2
                                                                      h.\1\
3. Acrylonitrile/styrene          0.10 ppm          17.4 to 19 pct.  Total nonvolatile   Maximum carbon dioxide
 copolymer consisting of the       (calculated on                     extractives not     permeability at 23
 copolymer produced by             the basis of                       to exceed 0.01 mg/  deg.C (73  deg.F) for
 polymerization of 66-72 parts     the weight of                      in \2\ surface      the finished article
 by weight of acrylonitrile and    the                                area of the food    is 0.04 barrer.\3\
 28-34 parts by weight of          acrylonitrile                      contact article
 styrene; for use with food of     copolymer resin                    when exposed to
 Types VI-A and VI-B identified    in the finished                    distilled water
 in table 1 of Sec.  176.170(c)    articles).\2\                      and 3 pct acetic
 of this chapter under                                                acid for 10 d at
 conditions of use C, D, E, F, G                                      66  deg.C (150
 described in table 2 of Sec.                                         deg.F).
 176.170(c) of this chapter.                                         The extracted
                                                                      copolymer shall
                                                                      not exceed 0.001
                                                                      mg/in \2\ surface
                                                                      area of the food
                                                                      contact article
                                                                      when exposed to
                                                                      distilled water
                                                                      and 3 pct acetic
                                                                      acid for 10 d at
                                                                      66  deg.C (150
                                                                      deg.F).\1\.
----------------------------------------------------------------------------------------------------------------
\1\ Use methods for determination of residual acrylonitrile monomer content, maximum extractable fraction,
  number average molecular weight, and solution viscosity, titled: "Determination of Residual Acrylonitrile and
  Styrene Monomers-Gas Chromatographic Internal Standard Method"; "Infrared Spectrophotometric Determination
  of Polymer Extracted from Barex 210 Resin Pellets"; "Procedure for the Determination of Molecular Weights of
  Acrylonitrile/Styrene Copolymers," and "Analytical Method for 10% Solution Viscosity of Tyril," which are
  incorproated by reference. Copies are available from the Center for Food Safety and Applied Nutrition (HFS-
  200), 5100 Paint Branch Pkwy., College Park, MD 20740, or may be examined at the Office of the Federal
  Register, 800 North Capitol Street, NW., suite 700, Washington, DC 20408.
 
[[Page 238]]
 
 
\2\ As determined by the method titled "Headspace Sampling and Gas-Solid Chromatographic Determination of
  Residual Acrylonitrile in Acrylonitrile Copolyemr Solutions," which is incorporated by reference. Copies are
  available from the Center for Food Safety and Applied Nutrition (HFS-200), 5100 Paint Branch Pkwy., College
  Park, MD 20740, or may be examined at the Office of the Federal Register, 800 North Capitol Street, NW., suite
  700, Washington, DC 20408.
\3\ As determined on appropriately shaped test samples of the article or acrylonitrile copolymer layer in a
  multilayer construction by ASTM method D-1434-82, "Standard Method for Determining Gas Permeability
  Characteristics of Plastic Film and Sheeting," which is incorporated by reference. Copies are available from
  the Center for Food Safety and Applied Nutrition (HFS-200), 5100 Paint Branch Pkwy., College Park, MD 20740,
  and the American Society for Testing Materials, 1916 Race Street, Philadelphia, PA 19103, or may be examined
  at the Office of the Federal Register, 800 North Capitol Street, NW., suite 700, Washington, DC 20408.
 
    (d) Interim listing. Acrylonitrile copolymers identified in this 
section shall comply with the provisions of Sec. 180.22 of this chapter.
    (e) Acrylonitrile copolymer identified in this section may be used 
to fabricate beverage containers only if they comply with the 
specifications of item 3 in paragraph (c) of this section.
 
[42 FR 14572, Mar. 15, 1977, as amended at 42 FR 48543, Sept. 23, 1977; 
47 FR 11841, Mar. 19, 1982; 49 FR 36643, Sept. 19, 1984; 52 FR 33803, 
Sept. 8, 1987]
 
 
 
 
 
[Code of Federal Regulations]
[Title 21, Volume 3]
[Revised as of April 1, 2003]
From the U.S. Government Printing Office via GPO Access
[CITE: 21CFR177.1050]
 
[Page 238-239]
 
                        TITLE 21--FOOD AND DRUGS
 
CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN 
                          SERVICES (CONTINUED)
 
PART 177--INDIRECT FOOD ADDITIVES: POLYMERS--Table of Contents
 
Subpart B--Substances for Use as Basic Components of Single and Repeated 
                        Use Food Contact Surfaces
 
Sec. 177.1050  Acrylonitrile/styrene copoly-mer modified with butadiene/styrene elastomer.
 
    Acrylonitrile/styrene copolymer modified with butadiene/styrene 
elastomer identified in this section may be safely used as a component 
of bottles intended for use with foods identified in table I of 
Sec. 176.170(c) of this chapter as Type VI-B under conditions for use E, 
F, or G described in table 2 of Sec. 176.170(c) of this chapter.
    (a) Identity. For the purpose of this section, acrylonitrile/styrene 
copoly- mer modified with butadiene/styrene elastomer consists of a 
blend of:
    (1) 82-88 parts by weight of a matrix copolymer produced by 
polymerization of 77-82 parts by weight of acrylonitrile and 18-23 parts 
of styrene; and
    (2) 12-18 parts by weight of a grafted rubber consisting of (i) 8-12 
parts of butadiene/styrene elastomer containing 77-82 parts by weight of 
butadiene and 18-23 parts by weight of styrene and (ii) 4-6 parts by 
weight of a graft copolymer consisting of 70-77 parts by weight of 
acrylonitrile and 23-30 parts by weight of styrene.
    (b) Adjuvants. The modified copoly-mer identified in paragraph (a) 
of this section may contain adjuvant substances required in its 
production. Such adjuvants may include substances generally recognized 
as safe in food, substances used in accordance with prior sanction, 
substances permitted under applicable regulations in this part, and the 
following:
 
------------------------------------------------------------------------
                Substances                           Limitations
------------------------------------------------------------------------
n-Dodecylmercaptan........................  The finished copolymer shall
                                             contain not more than 500
                                             parts per million (ppm)
                                             dodecylmercaptan as
                                             dodecylmercapto-
                                             propionitrile as determined
                                             by the method titled,
                                             "Determination of [beta]-
                                             Dodecyl-
                                             mercaptopropionitrile in NR-
                                             16 Polymer," which is
                                             incorporated by reference.
                                             Copies are available from
                                             the Center for Food Safety
                                             and Applied Nutrition (HFS-
                                             200), Food and Drug
                                             Administration, 5100 Paint
                                             Branch Pkwy., College Park,
                                             MD 20740, or available for
                                             inspection at the Office of
                                             the Federal Register, 800
                                             North Capitol Street, NW.,
                                             suite 700, Washington, DC
                                             20408.
------------------------------------------------------------------------
 
    (c) Specifications. (1) Nitrogen content of the modified copolymer 
is in the range of 17.7-19.8 percent.
    (2) Intrinsic viscosity of the matrix copolymer in butyrolactone is 
not less than 0.5 deciliter/gram at 35  deg.C, as determined by the 
method titled "Molecular Weight of Matrix Copolymer by Solution 
Viscosity," which is incorporated by reference. Copies are available 
from the Center for Food Safety and Applied Nutrition (HFS-200), Food 
and Drug Administration, 5100 Paint Branch Pkwy., College Park, MD 
20740, or available for inspection at the Office of the Federal 
Register, 800 North Capitol Street, NW., suite 700, Washington, DC 
20408.
    (3) Residual acrylonitrile monomer content of the modified copolymer 
articles is not more than 11 ppm as determined by a gas chromatographic 
method titled "Determination of Residual Acrylonitrile and Styrene 
Monomers-Gas Chromatographic Internal Standard Method," which is 
incorporated by
 
[[Page 239]]
 
reference. Copies are available from the Center for Food Safety and 
Applied Nutrition (HFS-200), Food and Drug Administration, 5100 Paint 
Branch Pkwy., College Park, MD 20740, or available for inspection at the 
Office of the Federal Register, 800 North Capitol Street, NW., suite 
700, Washington, DC 20408.
    (d) Extractives limitations. The following extractives limitations 
are determined by an infrared spectrophotometric method titled 
"Infrared Spectrophotometric Determination of Polymer Extracted from 
Borex[reg] 210 Resin Pellets," which is incorporated by reference. 
Copies are available from the Center for Food Safety and Applied 
Nutrition (HFS-200), Food and Drug Administration, 5100 Paint Branch 
Pkwy., College Park, MD 20740, or available for inspection at the Office 
of the Federal Register, 800 North Capitol Street, NW., suite 700, 
Washington, DC 20408, and are applicable to the modified copolymers in 
the form of particles of a size that will pass through a U.S. Standard 
Sieve No. 6 and that will be held on a U.S. Standard Sieve No. 10:
    (1) The extracted copolymer shall not exceed 2.0 ppm in aqueous 
extract obtained when a 100-gram sample of copolymer is extracted with 
250 milliliters of freshly distilled water at reflux temperature for 2 
hours.
    (2) The extracted copolymer shall not exceed 0.5 ppm in n-heptane 
when a 100-gram sample of the basic copol-ymer is extracted with 250 
milliliters spectral grade n-heptane at reflux temperature for 2 hours.
    (e) Accelerated extraction end test. The modified copolymer shall 
yield acrylonitrile monomer not in excess of 0.4 ppm when tested as 
follows:
    (1) The modified copolymer shall be in the form of eight strips \1/
2\ inch by 4 inches by .03 inch.
    (2) The modified copolymer strips shall be immersed in 225 
milliliters of 3 percent acetic acid in a Pyrex glass pressure bottle.
    (3) The pyrex glass pressure bottle is then sealed and heated to 150 
 deg.F in either a circulating air oven or a thermostat controlled bath 
for a period of 8 days.
    (4) The Pyrex glass pressure bottle is then removed from the oven or 
bath and cooled to room temperature. A sample of the extracting solvent 
is then withdrawn and analyzed for acrylonitrile monomer by a gas 
chromatographic method titled "Gas-Solid Chromatographic Procedure for 
Determining Acrylonitrile Monomer in Acrylonitrile-Containing Polymers 
and Food Simulating Solvents," which is incorporated by reference. 
Copies, are available from the Center for Food Safety and Applied 
Nutrition (HFS-200), Food and Drug Administration, 5100 Paint Branch 
Pkwy., College Park, MD 20740, or available for inspection at the Office 
of the Federal Register, 800 North Capitol Street, NW., suite 700, 
Washington, DC 20408.
    (f) Acrylonitrile copolymers identified in this section shall comply 
with the provisions of Sec. 180.22 of this chapter.
    (g) Acrylonitrile copolymers identified in this section are not 
authorized to be used to fabricate beverage containers.
 
[42 FR 14572, Mar. 15, 1977, as amended at 42 FR 48544, Sept. 23, 1977; 
47 FR 11841, Mar. 19, 1982; 47 FR 16775, Apr. 20, 1982; 54 FR 24898, 
June 12, 1989]
 
 
 
 
 
[Code of Federal Regulations]
[Title 21, Volume 3]
[Revised as of April 1, 2003]
From the U.S. Government Printing Office via GPO Access
[CITE: 21CFR177.1060]
 
[Page 239-240]
 
                        TITLE 21--FOOD AND DRUGS
 
CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN 
                          SERVICES (CONTINUED)
 
PART 177--INDIRECT FOOD ADDITIVES: POLYMERS--Table of Contents
 
Subpart B--Substances for Use as Basic Components of Single and Repeated 
                        Use Food Contact Surfaces
 
Sec. 177.1060  n-Alkylglutarimide/acrylic copolymers.
 
    n-Alkylglutarimide/acrylic copolymers identified in this section may 
be safely used as articles or components of articles intended for use in 
contact with food subject to provisions of this section and part 174 of 
this chapter.
    (a) Identity. For the purpose of this section, n-alkylglutarimide/
acrylic copolymers are copolymers obtained by reaction of substances 
permitted by Sec. 177.1010(a) (1), (2), and (3) with the following 
substance: Monomethylamine (CAS Reg. No. 74-89-5), to form n-
methylglutarimide/acrylic copolymers.
    (b) Adjuvants. The copolymers identified in paragraph (a) of this 
section may contain adjuvant substances required in their production. 
The optional adjuvant substances required in the production of the basic 
polymer may include substances permitted for such use by applicable 
regulations, as set forth in part 174 of this chapter.
    (c) Specifications. Maximum nitrogen content of the copolymer 
determined
 
[[Page 240]]
 
by micro-Kjeldahl analysis, shall not exceed 8 percent.
    (d) Limitations. (1) The n-alkylglutarimide/acrylic copolymers in 
the finished form in which they shall contact food, when extracted with 
the solvent or solvents characterizing the type of food and under the 
conditions of time and temperature described in tables 1 and 2 of 
Sec. 176.170(c) of this chapter, shall yield extractives not to exceed 
the limitations of Sec. 177.1010(b) of this chapter, when prepared as 
strips, as described in Sec. 177.1010(c)(2) of this chapter.
    (2) The n-alkylglutarimide/acrylic copolymers shall not be used as 
polymer modifiers in vinyl chloride homo- or copolymers.
    (e) Conditions of use. The n-alkylglutarimide/acrylic copolymers are 
used as articles or components of articles (other than articles composed 
of vinyl chloride homo- or copolymers) intended for use in contact with 
all foods except beverages containing more than 8 percent alcohol under 
conditions of use D, E, F, and G as described in table 2 of 
Sec. 176.170(c) of this chapter.
 
[54 FR 20382, May 11, 1989, as amended at 58 FR 17098, Apr. 1, 1993]
 
 
 
 
 
[Code of Federal Regulations]
[Title 21, Volume 3]
[Revised as of April 1, 2003]
From the U.S. Government Printing Office via GPO Access
[CITE: 21CFR177.1200]
 
[Page 240-243]
 
                        TITLE 21--FOOD AND DRUGS
 
CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN 
                          SERVICES (CONTINUED)
 
PART 177--INDIRECT FOOD ADDITIVES: POLYMERS--Table of Contents
 
Subpart B--Substances for Use as Basic Components of Single and Repeated 
                        Use Food Contact Surfaces
 
Sec. 177.1200  Cellophane.
 
    Cellophane may be safely used for packaging food in accordance with 
the following prescribed conditions:
    (a) Cellophane consists of a base sheet made from regenerated 
cellulose to which have been added certain optional substances of a 
grade of purity suitable for use in food packaging as constituents of 
the base sheet or as coatings applied to impart desired technological 
properties.
    (b) Subject to any limitations prescribed in this part, the optional 
substances used in the base sheet and coating may include:
    (1) Substances generally recognized as safe in food.
    (2) Substances for which prior approval or sanctions permit their 
use in cellophane, under conditions specified in such sanctions and 
substances listed in Sec. 181.22 of this chapter.
    (3) Substances that by any regulation promulgated under section 409 
of the act may be safely used as components of cellophane.
    (4) Substances named in this section and further identified as 
required.
    (c) List of substances:
 
------------------------------------------------------------------------
                                         Limitations (residue and limits
                                             of addition expressed as
           List of substances             percent by weight of finished
                                              packaging cellophane)
------------------------------------------------------------------------
Acrylonitrile-butadiene copolymer        As the basic polymer.
 resins.
Acrylonitrile-butadiene-styrene              Do.
 copolymer resins.
Acrylonitrile-styrene copolymer resins.      Do.
Acrylonitrile-vinyl chloride copolymer       Do.
 resins.
N-Acyl sarcosines where the acyl group   For use only as release agents
 is lauroyl or stearoyl.                  in coatings at levels not to
                                          exceed a total of 0.3 percent
                                          by weight of the finished
                                          packaging cellophane.
Alkyl ketene dimers identified in Sec.
 176.120 of this chapter.
Aluminum hydroxide.....................
Aluminum silicate......................
Ammonium persulfate....................
Ammonium sulfate.......................
Behenamide.............................
Butadiene-styrene copolymer............  As the basic polymer.
1,3-Butanediol.........................
n-Butyl acetate........................  0.1 percent.
n-Butyl alcohol........................      Do.
Calcium ethyl acetoacetate.............
Calcium stearoyl-2-lactylate identified  Not to exceed 0.5 percent
 in Sec.  172.844 of this chapter.        weight of cellophane.
Carboxymethyl hydroxyethylcellulose
 polymer.
Castor oil, hydrogenated...............
Castor oil phthalate with adipic acid    As the basic polymer.
 and fumaric acid-diethylene glycol
 polyester.
Castor oil phthalate, hydrogenated.....  Alone or in combination with
                                          other phthalates where total
                                          phthalates do not exceed 5
                                          percent.
Castor oil, sulfonated, sodium salt....
Cellulose acetate butyrate.............
Cellulose acetate propionate...........
Cetyl alcohol..........................
Clay, natural..........................
 
[[Page 241]]
 
 
Coconut oil fatty acid (C12-C18)         For use only as an adjuvant
 diethanolamide, coconut oil fatty acid   employed during the processing
 (C12-C18) diethanolamine soap, and       of cellulose pulp used in the
 diethanolamine mixture having total      manufacture of cellophane base
 alkali (calculated as potassium          sheet.
 hydroxide) of 16-18% and having an
 acid number of 25-35.
Copal resin, heat processed............  As basic resin.
Damar resin............................
Defoaming agents identified in Sec.
 176.200 of this chapter.
Dialkyl ketones where the alkyl groups   Not to exceed a total of 0.35
 are lauryl or stearyl.                   percent.
Dibutylphthalate.......................  Alone or in combination with
                                          other phthalates where total
                                          phthalates do not exceed 5
                                          percent.
Dicyclohexyl phthalate.................      Do.
Diethylene glycol ester of the adduct
 of terpene and maleic anhydride.
Di(2-ethylhexyl) adipate...............
Di(2-ethylhexyl) phthalate.............  Alone or in combination with
                                          other phthalates where total
                                          phthalates do not exceed 5
                                          percent.
Diisobutyl phthalate...................      Do.
Dimethylcyclohexyl phthalate...........      Do.
Dimethyldialkyl (C8-C18) ammonium        0.005 percent for use only as a
 chloride.                                flocculant for slip agents.
Di-n-ocyltin bis (2-ethylhexyl maleate)  For use only as a stabilizer at
                                          a level not to exceed 0.55
                                          percent by weight of the
                                          coating solids in vinylidene
                                          chloride copolymer waterproof
                                          coatings prepared from
                                          vinylidene chloride copolymers
                                          identified in this paragraph,
                                          provided that such vinylidene
                                          chloride copolymers contain
                                          not less than 90 percent by
                                          weight of polymer units
                                          derived from vinylidene
                                          chloride.
N,N'-Dioleoyethylenediamine, N,N'-       0.5 percent.
 dilinoleoylethylene-diamine and N-
 oleoyl-N'linoleoylethylene-diamine
 mixture produced when tall oil fatty
 acids are made to react with
 ethylenediamine such that the finished
 mixture has a melting point of 212
 deg.-228  deg.F., as determined by
 ASTM method D127-60 ("Standard Method
 of Test for Melting Point of
 Petrolatum and Microcrystalline Wax"
 (Revised 1960), which is incorporated
 by reference; copies are available
 from University Microfilms
 International, 300 N. Zeeb Rd., Ann
 Arbor, MI 48106, or available for
 inspection at the Office of the
 Federal Register, 800 North Capitol
 Street, NW., suite 700, Washington, DC
 20408), and an acid value of 10
 maximum.
N,N'-Dioleoylethylenediamine (N,N'-
 ethylenebisoleamide).
Disodium EDTA..........................
Distearic acid ester of                  0.06 percent.
 di(hydroxyethyl) diethylenetriamine
 monoacetate.
N,N'-Distearoylethylenediamine (N,N'-
 ethylenebis stearamide).
Epoxidized polybutadiene...............  For use only as a primer
                                          subcoat to anchor surface
                                          coatings to the base sheet.
Erucamide..............................
Ethyl acetate..........................
Ethylene-vinyl acetate copolymers
 complying with Sec.  177.1350.
2-Ethylhexyl alcohol...................  0.1 percent for use only as
                                          lubricant.
Fatty acids derived from animal and
 vegetable fats and oils, and the
 following salts of such acids, single
 or mixed: Aluminum, ammonium, calcium,
 magnesium, potassium, sodium.
Ferrous ammonium sulfate...............
Fumaric acid...........................
Glycerin-maleic anhydride..............  As the basic polymer.
Glycerol diacetate.....................
Glycerol monoacetate...................
Hydroxyethyl cellulose, water-insoluble
Hydroxypropyl cellulose identified in
 Sec.  172.870 of this chapter.
Isopropyl acetate......................  Residue limit 0.1 percent
Isopropyl alcohol......................      Do.
Itaconic acid..........................
Lanolin................................
Lauryl alcohol.........................
Lauryl sulfate salts: ammonium,
 magnesium, potassium, sodium.
Maleic acid............................  1 percent.
Maleic acid adduct of butadienestyrene
 copolymer.
Melamine formaldehyde..................  As the basic polymer.
 
[[Page 242]]
 
 
Melamine-formaldehyde modified with one  As the basic polymer, and used
 or more of the following: Butyl          as a resin to anchor coatings
 alcohol, diaminopropane,                 to substrate.
 diethylenetriamine, ethyl alcohol,
 guanidine, imino-bis-butylamine, imino-
 bis-ethylamine, imino-bis-propylamine,
 methyl alcohol, polyamines made by
 reacting ethylenediamine or
 trimethylenediamine with
 dichloroethane or dichloropropane,
 sulfanilic acid,
 tetraethylenepentamine,
 triethanolamine, triethylenetetra-mine.
Methyl ethyl ketone....................  Residue limit 0.1 percent
Methyl hydrogen siloxane...............  0.1 percent as the basic
                                          polymer.
[alpha]-Methylstyrene-vinyltoluene
 copolymer resins (molar ratio 1[alpha]-
 methylstyrene to 3 vinyltoluene).
Mineral oil, white.....................
Mono- and bis-(octadecyldiethylene       For use only as a release agent
 oxide) phosphates (CAS Reg. No. 62362-   at a level not to exceed 0.6
 49-6).                                   percent by weight of coatings
                                          for cellophane.
Naphthalenesulfonic acid-formaldehyde    0.1 percent, for use only as an
 condensate, sodium salt.                 emulsifier.
Nitrocellulose, 10.9 percent-12.2
 percent nitrogen.
Nylon resins complying with Sec.
 177.1500.
n-Octyl alcohol........................  For use only as a defoaming
                                          agent in the manufacture of
                                          cellophane base sheet.
Olefin copolymers complying with Sec.
 177.1520.
Oleic acid reacted with N-alkyl
 trimethylenediamine (alkyl C16 to C18).
Oleic acid, sulfonated, sodium salt....
Oleyl palmitamide......................
N,N'-Oleoyl-stearylethylenediamine (N-
 (2-stearoyl-aminoethyl)oleamide).
Paraffin, synthetic, complying with
 Sec.  175.250 of this chapter.
Pentaerythritol tetrastearate..........  0.1 percent.
Polyamide resins derived from dimerized  For use only in cellophane
 vegetable oil acids (containing not      coatings that contact food at
 more than 20 percent of monomer acids)   temperatures not to exceed
 and ethylenediamine as the basic resin.  room temperature.
Polyamide resins having a maximum acid   As the basic resin, for use
 value of 5 and a maximum amine value     only in coatings that contact
 of 8.5 derived from dimerized            food at temperatures not to
 vegetable oil acids (containing not      exceed room temperature
 more than 10 percent monomer acids),     provided that the
 ethylenediamine, and 4,4-bis(4-          concentration of the polyamido
 hydroxyphenyl)pentanoic acid (in an      resins in the finished food-
 amount not to exceed 10 percent by       contact coating does not
 weight of said polyamide resins).        exceed 5 milligrams per square
                                          inch of food-contact surface.
Polybutadiene resin (molecular weight    For use only as an adjuvant in
 range 2,000-10,200; bromine number       vinylidene chloride copolymer
 range 210-320).                          coatings.
Polycarbonate resins complying with
 Sec.  177.1580.
Polyester resin formed by the reaction
 of the methyl ester of rosin, phthalic
 anhydride, maleic anhydride, and
 ethylene glycol, such that the
 polyester resin has an acid number of
 4 to 11, a drop-softening point of 70
 deg.C-92  deg.C, and a color of K or
 paler.
Polyethylene...........................
Polyethyleneaminostearamide ethyl        0.1 percent.
 sulfate produced when stearic acid is
 made to react with equal parts of
 diethylenetriamine and
 triethylenetetramine and the reaction
 product is quaternized with diethyl
 sulfate.
Polyethylene glycol (400) monolaurate..
Polyethylene glycol (600) monolaurate..
Polyethylene glycol (400) monooleate...
Polyethylene glycol (600) monooleate...
Polyethylene glycol (400) monostearate.
Polyethylene glycol (600) monostearate.
Polyethylene, oxidized: complying with
 the identity prescribed in Sec.
 177.1620(a).
Polyethylenimine.......................  As the basic polymer, for use
                                          as a resin to anchor coatings
                                          to the substrate and for use
                                          as an impregnant in the food-
                                          contact surface of regenerated
                                          cellulose sheet in an amount
                                          not to exceed that required to
                                          improve heat-sealable bonding
                                          between coated and uncoated
                                          sides of cellophane.
Polyisobutylene complying with Sec.
 177.1420.
Polyoxypropylene-polyoxyethylene block   For use as an adjuvant employed
 polymers (molecular weight 1,900-        during the processing of
 9,000).                                  cellulose pulp used in the
                                          manufacture of cellophane base
                                          sheet.
Polypropylene complying with Sec.
 177.1520.
Polystyrene............................  As the basic polymer.
Polyvinyl acetate......................      Do.
 
[[Page 243]]
 
 
Polyvinyl alcohol (minimum viscosity of
 4 percent aqueous solution at 20
 deg.C of 4 centipoises).
Polyvinyl chloride.....................  As the basic polymer.
Polyvinyl stearate.....................      Do.
n-Propyl acetate.......................  Residue limit 0.1 percent.
n-Propyl alcohol.......................      Do.
Rapeseed oil, blown....................
Rosins and rosin derivatives as
 provided in Sec.  178.3870 of this
 chapter.
Rubber, natural (natural latex solids).
Silica.................................
Silicic acid...........................
Sodium m-bisulfite.....................
Sodium dioctyl sulfosuccinate..........
Sodium dodecylbenzenesulfonate.........
Sodium lauroyl sarcosinate.............  0.35 percent; for use only in
                                          vinylidene chloride copolymer
                                          coatings.
Sodium oleyl sulfate-sodium cetyl        For use only as an emulsifier
 sulfate mixture.                         for coatings; limit 0.005
                                          percent where coating is
                                          applied to one side only and
                                          0.01 percent where coating is
                                          applied to both sides.
Sodium silicate........................
Sodium stearoyl-2-lactylate identified   Not to exceed 0.5 percent
 in Sec.  172.846 of this chapter.        weight of cellophane.
Sodium sulfate.........................
Sodium sulfite.........................
Spermaceti wax.........................
Stannous oleate........................
2-Stearamido-ethyl stearate............
Stearyl alcohol........................
Styrene-maleic anhydride resins........  As the basic polymer.
Terpene resins identified in Sec.
 172.615 of this chapter.
Tetrahydrofuran........................  Residue limit of 0.1 percent.
Titanium dioxide.......................
Toluene................................  Residue limit of 0.1 percent.
Toluene sulfonamide formaldehyde.......  0.6 percent as the basic
                                          polymer.
Triethylene glycol.....................
Triethylene glycol diacetate, prepared
 from triethylene glycol containing not
 more than 0.1 percent of diethylene
 glycol.
2,2,4-Trimethyl-1,3 pentanediol          For use only in cellophane
 diisobutyrate.                           coatings and limited to use at
                                          a level not to exceed 10
                                          percent by weight of the
                                          coating solids except when
                                          used as provided in Sec.
                                          178.3740 of this chapter
Urea (carbamide).......................
Urea formaldehyde......................  As the basic polymer.
Urea formaldehyde modified with          As the basic polymer, and used
 methanol, ethanol, butanol               as a resin to anchor coatings
 diethylenetriamine,                      to the substrate.
 triethylenetetramine,
 tetraethylenepenta-mine, guanidine,
 sodium sulfite, sulfanilic acid, imino-
 bis-ethylamine, imino-bis-propylamine,
 imino-bis-butylamine, diaminopropane,
 diaminobutane, aminomethylsulfonic
 acid, polyamines made by reacting
 ethylenediamine or trimethylenediamine
 with dichlorethane or dichloropropane.
Vinyl acetate-vinyl chloride copolymer   As the basic polymer.
 resins.
Vinyl acetate-vinyl chloride-maleic          Do.
 acid copolymer resins.
Vinylidene chloride copolymerized with       Do.
 one or more of the following: Acrylic
 acid, acrylonitrile, butyl acrylate,
 butyl methacrylate, ethyl acrylate, 2-
 ethylhexyl acrylate, 2-ethylhexyl
 methacrylate, ethyl methacrylate,
 itaconic acid, methacrylic acid,
 methyl acrylate, methyl methacrylate,
 propyl acrylate, propyl methacrylate,
 vinyl chloride.
Vinylidene chloride-methacrylate             Do.
 decyloctyl copolymer.
Wax, petroleum, complying with Sec.
 178.3710 of this chapter.
------------------------------------------------------------------------
 
    (d) Any optional component listed in this section covered by a 
specific food additive regulation must meet any specifications in that 
regulation.
    (e) Acrylonitrile copolymers identified in this section shall comply 
with the provisions of Sec. 180.22 of this chapter.
 
[42 FR 14572, Mar. 15, 1977, as amended at 47 FR 11842, Mar. 19, 1982; 
64 FR 57978, Oct. 28, 1999]
 
[[Page 244]]
 
 
 
 
 
[Code of Federal Regulations]
[Title 21, Volume 3]
[Revised as of April 1, 2003]
From the U.S. Government Printing Office via GPO Access
[CITE: 21CFR177.1210]
 
[Page 244-247]
 
                        TITLE 21--FOOD AND DRUGS
 
CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN 
                          SERVICES (CONTINUED)
 
PART 177--INDIRECT FOOD ADDITIVES: POLYMERS--Table of Contents
 
Subpart B--Substances for Use as Basic Components of Single and Repeated 
                        Use Food Contact Surfaces
 
Sec. 177.1210  Closures with sealing gaskets for food containers.
 
    Closures with sealing gaskets may be safely used on containers 
intended for use in producing, manufacturing, packing, processing, 
preparing, treating, packaging, transporting, or holding food in 
accordance with the following prescribed conditions:
    (a) Closures for food containers are manufactured from substances 
generally recognized as safe for contact with food; substances that are 
subject to the provisions of prior sanctions; substances authorized by 
regulations in parts 174, 175, 176, 177, 178 and Sec. 179.45 of this 
chapter; and closure-sealing gaskets, as further prescribed in this 
section.
    (b) Closure-sealing gaskets and overall discs are formulated from 
substances identified in Sec. 175.300(b) of this chapter, with the 
exception of paragraph (b)(3) (v), (xxxi), and (xxxii) of that section, 
and from other optional substances, including the following:
    (1) Substances generally recognized as safe in food.
    (2) Substances used in accordance with the provisions of a prior 
sanction or approval within the meaning of section 201(s) of the act.
    (3) Substances that are the subject of regulations in parts 174, 
175, 176, 177, 178 and Sec. 179.45 of this chapter and used in 
accordance with the conditions prescribed.
    (4) Substances identified in paragraph (b)(5) of this section, used 
in amounts not to exceed those required to accomplish the intended 
physical or technical effect and in conformance with any limitation 
provided; and further provided that any substance employed in the 
production of closure-sealing gasket compositions that is the subject of 
a regulation in parts 174, 175, 176, 177, 178 and Sec. 179.45 of this 
chapter conforms with the identity or specifications prescribed.
    (5) Substances that may be employed in the manufacture of closure-
sealing gaskets include:
 
                                 Table 1
------------------------------------------------------------------------
                                            Limitations (expressed as
           List of substances             percent by weight of closure-
                                           sealing gasket composition)
------------------------------------------------------------------------
Arachidy-l-behenyl amide (C20-C22fatty   5 percent.
 acid amides).
Azodicarbonamide.......................  1. 2 percent.
                                         2. 5 percent; for use only in
                                          the manufacture of
                                          polyethylene complying with
                                          item 2.1 in Sec.  177.1520(c)
                                          of this chapter.
Balata rubber..........................
Benzyl alcohol.........................  1 percent.
Brominated isobutylene-isoprene
 copolymers, produced when isobutylene-
 isoprene copolymers complying with
 Sec.  177.1420(a)(2) are modified by
 bromination with not more than 2.3
 weight-percent of bromine and having a
 Mooney Viscosity (ML 1+8 (125  deg.C))
 of 27 or higher. The viscosity is
 determined by the American Society for
 Testing and Materials (ASTM) method D
 1646-81, "Standard Test Method for
 Rubber--Viscosity and Vulcanization
 Characteristics (Mooney Viscometer),"
 which is incorporated by reference in
 accordance with 5 U.S.C. 522(a) and 1
 CFR part 51. Copies are available from
 the Association of Official Analytical
 Chemists International, 481 North
 Frederick Ave., Suite 500,
 Gaithersburg, MD 20877-2504 and the
 Center for Food Safety and Applied
 Nutrition (HFS-200), Food and Drug
 Administration, 5100 Paint Branch
 Pkwy., College Park, MD 20740, or
 available for inspection at the Office
 of the Federal Register, 800 North
 Capitol Street, NW., suite 700,
 Washington, DC.
1,3-Butanediol.........................
Calcium tin stearate...................  2 percent.
Calcium zinc stearate..................      Do.
Carbon, activated......................  1 percent.
Castor oil, hydrogenated...............  2 percent.
Chlorinated isobutylene-isoprene
 copolymers complying with Sec.
 177.1420.
Coco amide (coconut oil fatty acids      2 percent.
 amides).
Cork (cleaned, granulated).............
Diebenzamide phenyl disulfide..........  1 percent; for use only in
                                          vulcanized natural or
                                          synthetic rubber gasket
                                          compositions.
 
[[Page 245]]
 
 
Di(C7, C9-alkyl) adipate...............  Complying with Sec.  178.3740
                                          of this chapter; except that,
                                          there is no limitation on
                                          polymer thickness.
Di-2-ethylhexyl adipate................
Di-2-ethylhexyl sebacate...............  2 percent.
Di-2-ethylhexyl terephthalate (CAS Reg.  For use as a plasticizer at
 No. 006422-86-2)..                       levels not exceeding 75 parts
                                          per hundred by weight of
                                          permitted vinyl chloride homo-
                                          and/or copolymer resins used
                                          in contact with food of Types
                                          I, II, IV-B, VI-A, VI-B, VI-C
                                          (up to 15 percent alcohol by
                                          volume), VII-B, and VIII
                                          described in Sec.  176.170(c)
                                          of this chapter, table 1, and
                                          under conditions of use A
                                          through H described in Sec.
                                          176. 170 (c) of this chapter,
                                          table 2.
Dihexyl ester of sodium sulfosuccinate.  1 percent.
Diisodecyl phthalate...................  No limitation on amount used
                                          but for use only in closure-
                                          sealing gasket compositions
                                          used in contact with non-fatty
                                          foods containing no more than
                                          8 percent of alcohol.
Di-[beta]-naphthyl-p-phenylenediamine..  1 percent.
Dipentamethylenethiurametetrasulfide...  0.4 percent; for use only in
                                          vulcanized natural or
                                          synthetic rubber gasket
                                          compositions.
Eicosane (technical grade) (water-white
 mixture of predominantly straight-
 chain paraffin hydrocarbons averaging
 20 carbon atoms per molecule).
Epoxidized linseed oil.................
Epoxidized linseed oil modified with
 trimellitic anhydride.
Epoxidized safflower oil...............
Epoxidized safflower oil modified with
 trimellitic anhydride.
Epoxidized soybean oil modified with
 trimellitic anhydride.
Erucylamide............................  5 percent.
Ethylene-propylene copolymer...........
Ethylene-propylene modified copolymer
 elastomers produced when ethylene and
 propylene are copolymerized with 5-
 methylene-2-norbornene and/or 5-
 ethylidine-2-norbornene. The finished
 copolymer elastomers so produced shall
 contain not more than 5 weight-percent
 of total polymer units derived from 5-
 methylene-2-norbornene and/or 5-
 ethylidine-2-norbornene, and shall
 have a minimum viscosity average
 molecular weight of 120,000 as
 determined by the method described in
 Sec.  177.1520(d)(5), and a minimum
 Mooney viscosity of 35 as determined
 by the method described in Sec.
 177.1520(d)(6).
Ethylene-vinyl acetate copolymer.......
Glyceryl mono-12-hydroxystearate         2 percent.
 (hydrogenated glyceryl ricinoleate).
Gutta-percha...........................
Hexamethylenetetramine.................  1 percent.
Hexylene glycol........................  0.5 percent.
Isobutylene-isoprene copolymers
 complying with Sec.  177.1420.
Maleic anhydride-polyethylene copolymer  5 percent.
Maleic anhydride-styrene copolymer.....      Do.
2,2'-Methylenebis[6-(1-                  1 percent.
 methylcylcohexyl)-p-cresol].
Mixed octylated diphenylamine (CAS Reg.  0.1 percent in isobutylene-
 No. 68411-46-1).                         isoprene and chlorinated
                                          isobutylene-isoprene
                                          copolymers complying with Sec.
                                           177.1420, and brominated
                                          isobutylene-isoprene
                                          copolymers complying with this
                                          section.
Napthalene sulfonic acid-formaldehyde    0.2 percent.
 condensate, sodium salt.
Natural rubber (crepe, latex,
 mechanical dispersions).
[alpha]-cis-9-Octadecenyl-omega-         0.5 percent.
 hydroxypoly (oxyethylene); the
 octadecenyl group is derived from
 oleyl alcohol and the poly
 (oxyethylene) content averages 20
 moles.
Oleyl alcohol..........................  1 percent.
4,4'-Oxybis (benzene sulfonyl            0.5 percent.
 hydrazide).
Paraformaldehyde.......................  1 percent.
Polybutadiene..........................
Poly-p-dinitroso benzene (activator for  1 percent; for use only in
 butyl rubber).                           vulcanized natural or
                                          synthetic rubber gasket
                                          compositions.
Polyethylene glycol 400 esters of fatty  1 percent.
 acids derived from animal and
 vegetable fats and oils.
Polyisobutylene complying with Sec.
 177.1420.
Polyoxypropylene-polyoxyethylene         0.05 percent.
 condensate, average mol. wt. 2750-3000.
 
[[Page 246]]
 
 
Polyurethane resins manufactured from    For use only:
 diphenylmethane diisocyanate, 1,4-        No limitation on amount used,
 butanediol, and adipic acid (CAS Reg.    but for use only in closure
 No. 26375-23-5)..                        gasket compositions used in
                                          contact with food types VI-A
                                          and VI-C (up to 15 percent
                                          alcohol) under conditions of
                                          use D, E, F, and G, as
                                          described in Sec.  176.170(c)
                                          of this chapter, tables 1 and
                                          2, respectively.
Potassium benzoate.....................  1 percent.
Potassium perchlorate..................      Do.
Potassium propionate...................  2 percent.
Potassium and sodium persulfate........  1 percent.
Resorcinol.............................  0.24 percent; for use only as a
                                          reactive adjuvant substance
                                          employed in the production of
                                          gelatin-bonded cord
                                          compositions for use in lining
                                          crown closures. The gelatin so
                                          used shall be technical grade
                                          or better.
Rosins and rosin derivatives as defined
 in Sec.  175.300(b)(3)(v) of this
 chapter for use only in resinous and
 polymeric coatings on metal
 substrates; for all other uses as
 defined in Sec.  178.3870 of this
 chapter.
Sodium cetyl sulfate...................  1 percent.
Sodium decylbenzenesulfonate...........      Do.
Sodium decyl sulfate...................      Do.
Sodium formaldehyde sulfoxylate........  0.05 percent.
Sodium lauryl sulfate..................  1 percent.
Sodium lignin sulfonate................  0.2 percent.
Sodium myristyl sulfate (sodium          0.6 percent.
 tetradecyl sulfate).
Sodium nitrite.........................  0.2 percent; for use only in
                                          annular ring gaskets applied
                                          in aqueous dispersions to
                                          closures for containers having
                                          a capacity of not less than 5
                                          gallons.
Sodium o-phenylphenate.................  0.05 percent.
Sodium polyacrylate....................  5 percent.
Sodium and potassium pentachlorophenate  0.05 percent.
Sodium salt of trisopropyl               0.2 percent.
 napthalenesulfonic acid.
Sodium tridecylsulfate.................  0.6 percent.
Stearic acid amide.....................  5 percent.
Sulfur.................................  For use only as a vulcanizing
                                          agent in vulcanized natural or
                                          synthetic rubber gasket
                                          compositions at a level not to
                                          exceed 4 percent by weight of
                                          the elastomer content of the
                                          rubber gasket composition.
Tallow, sulfated.......................  1 percent.
Tin-zinc stearate......................  2 percent.
Tri(mixed mono- and dinonylphenyl)       1 percent.
 phosphite.
Vinyl chloride-vinyl stearate copolymer
Zinc dibutyldithiocarbamate............  0.8 percent; for use only in
                                          vulcanized natural or
                                          synthetic rubber gasket
                                          compositions.
------------------------------------------------------------------------
 
 
                                     Table 2--Maximum Extractives Tolerances
                                             [In parts per million]
----------------------------------------------------------------------------------------------------------------
                                                                            Chloroform   Chloroform   Chloroform
                                                                           fraction of  fraction of  fraction of
                Type of closure-sealing gasket composition                    water       heptane      alcohol
                                                                           extractives  extractives  extractives
----------------------------------------------------------------------------------------------------------------
1. Plasticized polymers, including unvulcanized or vulcanized or                   50          500           50
 otherwise cured natural and synthetic rubber formed in place as overall
 discs or annular rings from a hot melt, solution, plastisol, organisol,
 mechanical dispersion, or latex.........................................
2. Preformed overall discs or annular rings of plasticized polymers,               50          250           50
 including unvulcanized natural or synthetic rubber......................
3. Preformed overall discs or annular rings of vulcanized plasticized              50           50           50
 polymers, including natural or synthetic rubber.........................
4. Preformed overall discs or annular rings of polymeric or resinous-              50          250           50
 coated paper, paperboard, plastic, or metal foil substrates.............
5. Closures with sealing gaskets or sealing compositions as described in        (\1\)        (\1\)        (\1\)
 1, 2, 3, and 4, and including paper, paperboard, and glassine used for
 dry foods only..........................................................
----------------------------------------------------------------------------------------------------------------
\1\ Extractability tests not applicable.
 
 
[[Page 247]]
 
    (c) The closure assembly to include the sealing gasket or sealing 
compound, together with any polymeric or resinous coating, film, foil, 
natural cork, or glass that forms a part of the food-contact surface of 
the assembly, when extracted on a suitable glass container with a 
solvent or solvents characterizing the type of foods, and under 
conditions of time and temperature characterizing the conditions of its 
use as determined from tables 3 and 4 shall yield net chloroform-soluble 
extractives (corrected for zinc as zinc oleate) not to exceed the 
tolerances specified in table 2, calculated on the basis of the water 
capacity of the container on which the closure is to be used. Employ the 
analytical method described in Sec. 175.300 of this chapter, adapting 
the procedural details to make the method applicable to closures; such 
as, for example, placing the closed glass container on its side to 
assure contact of the closure's food-contacting surface with the 
solvent.
 
                         Table 3--Types of Food
I. Nonacid (pH above 5.0), aqueous products; may contain salt or sugar
 or both, and including oil-in-water emulsions of low- or high-fat
 content.
II. Acidic (pH 5.0 or below), aqueous products; may contain salt or
 sugar or both, and including oil-in-water emulsions of low- or high-fat
 content.
III. Aqueous, acid or nonacid products containing free oil or fat; may
 contain salt, and including water-in-oil emulsions of low- or high-fat
 content.
IV. Dairy products and modifications:
  A. Water-in-oil emulsions, high- or low-fat.
  B. Oil-in-water emulsions, high- or low-fat.
V. Low-moisture fats and oils.
VI. Beverages:
  A. Containing alcohol.
  B. Nonalcoholic.
VII. Bakery products.
VIII. Dry solids (no end-test required).
 
 
 
  Table 4--Test Procedures With Time-Temperature Conditions for Determining Amount of Extractives From Closure-
                     Sealing Gaskets, Using Solvents Simulating Types of Foods and Beverages
----------------------------------------------------------------------------------------------------------------
                                                                              Extractant
                                  Types of food (see -----------------------------------------------------------
        Conditions of use              table 3)                                                8 percent alcohol
                                                           Water \2\         Heptane \1 2\            \2\
----------------------------------------------------------------------------------------------------------------
A. High temperature heat-         I, IV-B...........  250  deg.F, 2 hr..  ..................
 sterilized (e.g., over 212       III, IV-A, VII....  ......do..........  150  deg.F, 2 hr..
 deg.F).
B. Boiling water-sterilized.....  II................  212  deg.F, 30 min  ..................
                                  III, VII..........  ......do..........  120  deg.F, 30 min
C. Hot filled or pasteurized      II, IV-B..........  Fill boiling, cool  ..................
 above 150  deg.F.                III, IV-A.........   to 100  deg.F.     120  deg.F, 15 min
                                  V.................  ......do..........  ......do..........
D. Hot filled or pasteurized      II, IV-B, VI-B....  150  deg.F, 2 hr..  ..................  ..................
 below 150  deg.F.                III, IV-A.........  ......do..........  100  deg.F, 30 min  150  deg.F, 2 hr
                                  V.................                      .......do.........
                                  VI-A..............
E. Temperature filled and stored  II, IV-B, VI-B....  120  deg.F, 24 hr.  ..................  ..................
 (no thermal treatment in the     III, IV-A.........  ......do..........  70  deg.F, 30 min.  120  deg.F, 24 hr.
 container).                      V.................                      ......do..........
                                  VI-A..............
F. Refrigerated storage (no       I, II, III, IV-A,   70  deg.F, 48 hr..  70  deg.F, 30 min.  ..................
 thermal treatment).               IV-B, VI-B, VII.                                           70  deg.F, 48 hr.
                                  VI-A..............
G. Frozen storage (no thermal     I, II, III, IV-B,   70  deg.F, 24 hr..  ..................
 treatment in the container).      VII.
----------------------------------------------------------------------------------------------------------------
\1\ Heptane extractant not applicable to closure-sealing gaskets overcoated with wax.
\2\ Time and temperature.
 
 
[42 FR 14572, Mar. 15, 1977; 42 FR 56728, Oct. 28, 1977, as amended at 
47 FR 22090, May 21, 1982; 49 FR 5748, Feb. 15, 1984; 55 FR 34555, Aug. 
23, 1990; 61 FR 14480, Apr. 2, 1996; 65 FR 26745, May 9, 2000; 65 FR 
52908, Aug. 31, 2000]
 
 
 
 
 
[Code of Federal Regulations]
[Title 21, Volume 3]
[Revised as of April 1, 2003]
From the U.S. Government Printing Office via GPO Access
[CITE: 21CFR177.1211]
 
[Page 247-248]
 
                        TITLE 21--FOOD AND DRUGS
 
CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN 
                          SERVICES (CONTINUED)
 
PART 177--INDIRECT FOOD ADDITIVES: POLYMERS--Table of Contents
 
Subpart B--Substances for Use as Basic Components of Single and Repeated 
                        Use Food Contact Surfaces
 
Sec. 177.1211  Cross-linked polyacrylate copolymers.
 
    Cross-linked polyacrylate copolymers identified in paragraph (a) of 
this section may be safely used as articles or components of articles 
intended for use in contact with food in accordance with the following 
prescribed conditions:
    (a) Identity. For the purpose of this section, the cross-linked 
polyacrylate copolymers consist of:
 
[[Page 248]]
 
    (1) The grafted copolymer of cross-linked sodium polyacrylate 
identified as 2-propenoic acid, polymers with N,N-di-2-propenyl-2-
propen-1-amine and hydrolyzed polyvinyl acetate, sodium salts, graft 
(CAS Reg. No. 166164-74-5); or
    (2) 2-propenoic acid, polymer with 2-ethyl-2-(((1-oxo-2-
propenyl)oxy)methyl)-1,3-propanediyl di-2-propenoate and sodium 2-
propenoate (CAS Reg. No. 76774-25-9).
    (b) Adjuvants. The copolymers identified in paragraph (a) of this 
section may contain optional adjuvant substances required in the 
production of such copolymers. The optional adjuvant substances may 
include substances permitted for such use by regulations in parts 170 
through 179 of this chapter, substances generally recognized as safe in 
food, and substances used in accordance with a prior sanction or 
approval.
    (c) Extractives limitations. The copolymers identified in paragraph 
(a) of this section, in the finished form in which they will contact 
food, must yield low molecular weight (less than 1,000 Daltons) 
extractives of no more than 0.15 percent by weight of the total polymer 
when extracted with 0.2 percent by weight of aqueous sodium chloride 
solution at 20  deg.C for 24 hours. The low molecular weight extractives 
shall be determined using size exclusion chromatography or an equivalent 
method. When conducting the extraction test, the copolymer, with no 
other absorptive media, shall be confined either in a finished absorbent 
pad or in any suitable flexible porous article, (such as a "tea bag" 
or infuser), under an applied pressure of 0.15 pounds per square inch 
(for example, a 4x6 inch square pad is subjected to a 1.6 kilograms 
applied mass). The solvent used shall be at least 60 milliliters aqueous 
sodium chloride solution per gram of copolymer.
    (d) Conditions of use. The copolymers identified in paragraph (a)(1) 
of this section are limited to use as a fluid absorbent in food-contact 
materials used in the packaging of frozen or refrigerated poultry. The 
copolymers identified in paragraph (a)(2) of this section are limited to 
use as a fluid absorbent in food-contact materials used in the packaging 
of frozen or refrigerated meat and poultry.
 
[64 FR 28098, May 25, 1999, as amended at 65 FR 16817, Mar. 30, 2000]
 
 
 
 
 
[Code of Federal Regulations]
[Title 21, Volume 3]
[Revised as of April 1, 2003]
From the U.S. Government Printing Office via GPO Access
[CITE: 21CFR177.1240]
 
[Page 248-249]
 
                        TITLE 21--FOOD AND DRUGS
 
CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN 
                          SERVICES (CONTINUED)
 
PART 177--INDIRECT FOOD ADDITIVES: POLYMERS--Table of Contents
 
Subpart B--Substances for Use as Basic Components of Single and Repeated 
                        Use Food Contact Surfaces
 
Sec. 177.1240  1,4-Cyclohexylene dimethylene terephthalate and 1,4-cyclohexylene dimethylene isophthalate copolymer.
 
    Copolymer of 1,4-cyclohexylene dimethylene terephthalate and 1,4-
cyclohexylene dimethylene isophthalate may be safely used as an article 
or component of articles used in producing, manufacturing, packing, 
processing, preparing, treating, packaging, transporting, or holding 
food, subject to the provisions of this section:
    (a) The copolymer is a basic polyester produced by the catalytic 
condensation of dimethyl terephthalate and dimethyl isophthalate with 
1,4-cyclohexanedimethanol, to which may have been added certain optional 
substances required in its production or added to impart desired 
physical and technical properties.
    (b) The quantity of any optional substance employed in the 
production of the copolymer does not exceed the amount reasonably 
required to accomplish the intended physical or technical effect or any 
limitation further provided.
    (c) Any substance employed in the production of the copolymer that 
is the subject of a regulation in parts 174, 175, 176, 177, 178 and 
Sec. 179.45 of this chapter conforms with any specification in such 
regulation.
    (d) Substances employed in the production of the copolymer include:
    (1) Substances generally recognized as safe in food.
    (2) Substances subject to prior sanction or approval for use in the 
copoly-mer and used in accordance with such sanction or approval.
    (3) Substances which by regulation in parts 174, 175, 176, 177, 178 
and Sec. 179.45 of this chapter may be safely used as components of 
resinous or polymeric coatings and film used as food-contact surfaces, 
subject to the provisions of such regulation.
    (e) The copolymer conforms with the following specifications:
 
[[Page 249]]
 
    (1) The copolymer, when extracted with distilled water at reflux 
temperature for 2 hours, yields total extractives not to exceed 0.05 
percent.
    (2) The copolymer, when extracted with ethyl acetate at reflux 
temperature for 2 hours, yields total extractives not to exceed 0.7 
percent.
    (3) The copolymer, when extracted with n-hexane at reflux 
temperature for 2 hours, yields total extractives not to exceed 0.05 
percent.
 
[42 FR 14572, Mar. 15, 1977; 49 FR 5748, Feb. 15, 1984, as amended at 55 
FR 34555, Aug. 23, 1990]
 
 
 
 
 
[Code of Federal Regulations]
[Title 21, Volume 3]
[Revised as of April 1, 2003]
From the U.S. Government Printing Office via GPO Access
[CITE: 21CFR177.1310]
 
[Page 249]
 
                        TITLE 21--FOOD AND DRUGS
 
CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN 
                          SERVICES (CONTINUED)
 
PART 177--INDIRECT FOOD ADDITIVES: POLYMERS--Table of Contents
 
Subpart B--Substances for Use as Basic Components of Single and Repeated 
                        Use Food Contact Surfaces
 
Sec. 177.1310  Ethylene-acrylic acid copolymers.
 
    The ethylene-acrylic acid copolymers identified in paragraph (a) of 
this section may be safely used as components of articles intended for 
use in contact with food subject to the provisions of this section.
    (a) The ethylene-acrylic acid copolymers consist of basic copolymers 
produced by the copolymerization of ethylene and acrylic acid such that 
the finished basic copolymers contain no more than:
    (1) 10 weight-percent of total polymer units derived from acrylic 
acid when used in accordance with paragraph (b) of this section; and
    (2) 25 weight-percent of total polymer units derived from acrylic 
acid when used in accordance with paragraph (c) of this section.
    (b) The finished food-contact articles made with no more than 10 
percent total polymer units derived from acrylic acid, when extracted 
with the solvent or solvents characterizing the type of food and under 
the conditions of its intended use as determined from tables 1 and 2 of 
Sec. 176.170(c) of this chapter, yield net acidified chloroform-soluble 
extractives not to exceed 0.5 milligram per square inch of food-contact 
surface when tested by the methods prescribed in Sec. 177.1330(e)(1), 
(3)(i) through (iv), (4), (5), and (6), except that
    (1) The total residue method using 3 percent acetic acid, as 
prescribed in Sec. 177.1330(e)(6)(i)(a), does not apply, and
    (2) The net acidified chloroform-soluble extractives from paper and 
paperboard complying with Sec. 176.170 of this chapter may be corrected 
for wax, petrolatum, and mineral oil as provided in 
Sec. 176.170(d)(5)(iii)(b) of this chapter.
 
If the finished food-contact article is itself the subject of a 
regulation in parts 174, 175, 176, 177, 178, and Sec. 179.45 of this 
chapter, it shall also comply with any specifications and limitations 
prescribed for it by that regulation.
    (c) The finished food-contact layer made with basic copolymers 
containing more than 10 weight-percent but no more than 25 weight-
percent of total polymer units derived from acrylic acid and with a 
maximum thickness of 0.0025 inch (2.5 mils) may be used in contact with 
food types I, II, IVB, VIA, VIB, VIIB, and VIII identified in table 1 of 
Sec. 176.170(c) of the chapter under conditions of use B through H as 
described in table 2 of Sec. 176.170(c) of this chapter, and in contact 
with food types III, IVA, V, VIIA, and IX identified in table 1 of 
Sec. 176.170(c) of this chapter under conditions of use E through G as 
described in table 2 of Sec. 176.170(c) of this chapter.
    (d) The provisions of this section are not applicable to ethylene-
acrylic acid copolymers used in food-packaging adhesives complying with 
Sec. 175.105 of this chapter.
 
[42 FR 14572, Mar. 15, 1977, as amended at 51 FR 19060, May 27, 1986; 53 
FR 44009, Nov. 1, 1988]
 
 
 
 
 
[Code of Federal Regulations]
[Title 21, Volume 3]
[Revised as of April 1, 2003]
From the U.S. Government Printing Office via GPO Access
[CITE: 21CFR177.1312]
 
[Page 249-250]
 
                        TITLE 21--FOOD AND DRUGS
 
CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN 
                          SERVICES (CONTINUED)
 
PART 177--INDIRECT FOOD ADDITIVES: POLYMERS--Table of Contents
 
Subpart B--Substances for Use as Basic Components of Single and Repeated 
                        Use Food Contact Surfaces
 
Sec. 177.1312  Ethylene-carbon monoxide copolymers.
 
    The ethylene-carbon monoxide copolymers identified in paragraph (a) 
of this section may be safely used as components of articles intended 
for use in contact with food subject to the provisions of this section.
    (a) Identity. For the purposes of this section, ethylene-carbon 
monoxide copolymers (CAS Reg. No. 25052-62-4) consist of the basic 
polymers produced by the copolymerization of ethylene and carbon 
monoxide such that the copolymers contain not more than 30 weight-
percent of polymer units derived from carbon monoxide.
    (b) Conditions of use. (1) The polymers may be safely used as 
components of the food-contact or interior core layer of multilaminate 
food-contact articles.
    (2) The polymers may be safely used as food-contact materials at 
temperatures not to exceed 121  deg.C (250  deg.F).
 
[[Page 250]]
 
    (c) Specifications. (1) Food-contact layers formed from the basic 
copolymer identified in paragraph (a) of this section shall be limited 
to a thickness of not more than 0.01 centimeter (0.004 inch).
    (2) The copolymers identified in paragraph (a) of this section shall 
have a melt index not greater than 500 as determined by ASTM method 
D1238-82, condition E "Standard Test Method for Flow Rates of 
Thermoplastics by Extrusion Plastometer," which is incorporated by 
reference in accordance with 5 U.S.C. 552(a) and 1 CFR part 51. Copies 
may be obtained from the American Society for Testing Materials, 1916 
Race St., Philadelphia, PA 19103, or may be examined at the Center for 
Food Safety and Applied Nutrition (HFS-200), Food and Drug 
Administration, 5100 Paint Branch Pkwy., College Park, MD 20740, or at 
the Office of the Federal Register, 800 North Capitol St. NW., suite 
700, Washington, DC.
    (3) The basic copolymer identified in paragraph (a) of this section, 
when extracted with the solvent or solvents characterizing the type of 
food and under the conditions of time and temperature characterizing the 
conditions of its intended use, as determined from tables 1 and 2 of 
Sec. 176.170(c) of this chapter, yields net chloroform-soluble 
extractives in each extracting solvent not to exceed 0.5 milligram per 
square inch of food-contact surface when tested by methods described in 
Sec. 176.170(d) of this chapter.
    (4) The provisions of this section are not applicable to ethylene-
carbon monoxide copolymers complying with Sec. 175.105 of this chapter.
 
[57 FR 32422, July 22, 1992]
 
 
 
 
 
[Code of Federal Regulations]
[Title 21, Volume 3]
[Revised as of April 1, 2003]
From the U.S. Government Printing Office via GPO Access
[CITE: 21CFR177.1315]
 
[Page 250-253]
 
                        TITLE 21--FOOD AND DRUGS
 
CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN 
                          SERVICES (CONTINUED)
 
PART 177--INDIRECT FOOD ADDITIVES: POLYMERS--Table of Contents
 
Subpart B--Substances for Use as Basic Components of Single and Repeated 
                        Use Food Contact Surfaces
 
Sec. 177.1315  Ethylene-1, 4-cyclohexylene dimethylene terephthalate copolymers.
 
    Ethylene-1, 4-cyclohexylene dimethylene terephthalate copolymer may 
be safely used as articles or components of articles intended for use in 
contact with food subject to provisions of this section and of part 174 
of this chapter.
    (a) Identity. For the purposes of this section, ethylene-1,4-
cyclohexylene dimethylene terephthalate copolymers (1,4-benzene 
dicarboxylic acid, dimethyl ester, polymerized with 1,4-
cyclohexanedimethanol and 1,2-ethanediol) (CAS Reg. No. 25640-14-6) or 
(1,4-benzenedicarboxylic acid, polymerized with 1,4-
cyclohexanedimethanol and 1,2-ethanediol) (CAS Reg. No. 25038-91-9) are 
basic copolymers meeting the specifications prescribed in paragraph (b) 
of this section, to which may have been added certain optional 
substances required in their production or added to impart desired 
physical or technical properties.
    (b) Specifications:
 
[[Page 251]]
 
 
 
----------------------------------------------------------------------------------------------------------------
                                                            Maximum
                                                          extractable
                                                       fractions of the
                                                       copolymer in the
                                                       finished form at
   Ethylene-1,4-cyclohexylene                              specified
    dimethylene terephthalate     Inherent viscosity   temperatures and        Test for        Conditions of use
           copolymers                                  times (expressed      orientability
                                                       in micrograms of
                                                       the terephthaloyl
                                                        moletles/square
                                                      centimeter of food-
                                                       contact surface)
----------------------------------------------------------------------------------------------------------------
1. Non-oriented ethylene-1,4-     Inherent viscosity  (1) 0.23 microgram  No test required..  In contact with
 cyclohexylene dimethylene         of a 0.50 percent   per square                              foods, including
 terephthalate copolymer is the    solution of the     centimeter (1.5                         foods containing
 reaction product of dimethyl      copolymer in        micrograms per                          not more than 25
 terephthalate or terephthalic     phenol-tet          square inch) of                         percent (by
 acid with a mixture containing    rachloroethane      food-contact                            volume) aqueous
 99 to 66 mole percent of          (60:40 ratio wt/    surface when                            alcohol,
 ethylene glycol and 1 to 34       wt) solvent is      extracted with                          excluding
 mole percent of 1,4-cyclo-        not less than       water added at                          carbonated
 hexanedimethanol (70 percent      0.669 as            82.2  deg.C (180                        beverages and
 trans isomer, 30 percent cls      determined by       deg.F) and                              beer. Conditions
 isomer).                          using a Wagner      allowed to cool                         of hot fill not
                                   viscometer (or      to 48.9  deg.C                          to exceed 82.2
                                   equivalent) and     (120  deg.F) in                         deg.C (180
                                   calculated from     contact with the                        deg.F), storage
                                   the following       food-contact                            at temperatures
                                   equation:           article.                                not in excess of
                                   Inherent                                                    48.9  deg.C (120
                                   viscosity =                                                 deg.F). No
                                   (Natural                                                    thermal treatment
                                   logarithm of (Nr)/                                          in the container.
                                   (c) where:
                                   NrRatio of flow
                                   time of the
                                   polymer solution
                                   to that of the
                                   solvent, and
                                   c=concentration
                                   of the test
                                   solution
                                   expressed in
                                   grams per 100
                                   milliliters.
                                  ......do..........  (2) 0.23 microgram  ......do..........      Do.
                                                       per square
                                                       centimeter (1.5
                                                       micrograms per
                                                       square inch) of
                                                       food-contact
                                                       surface when
                                                       extracted with 3
                                                       percent (by
                                                       volume) aqueous
                                                       acetic acid added
                                                       at 82.2  deg.C
                                                       (180  deg.F) and
                                                       allowed to cool
                                                       to 48.9  deg.C
                                                       (120  deg.F) in
                                                       contact with the
                                                       food-contact
                                                       article.
                                  ......do..........  (3) 0.08 microgram  ......do..........      Do.
                                                       per square
                                                       centimeter (0.5
                                                       microgram per
                                                       square inch) of
                                                       food-contact
                                                       surface when
                                                       extracted for 2
                                                       hours with n-
                                                       heptane at 48.9
                                                       deg.C (120
                                                       deg.F). The
                                                       heptane
                                                       extractable
                                                       results are to be
                                                       divided by a
                                                       factor of 5.
                                  ......do..........  (4) 0.16 microgram  ......do..........      Do.
                                                       per square
                                                       centimeter (1.0
                                                       microgram per
                                                       square inch) of
                                                       food-contact
                                                       surface when
                                                       extracted for 24
                                                       hours with 25
                                                       percent (by
                                                       volume) aqueous
                                                       ethanol at 48.9
                                                       deg.C (120
                                                       deg.F).
 
[[Page 252]]
 
 
2. Oriented ethylene-1,4-         ......do..........  (1) 0.23 microgram  When extracted      In contact with
 cyclohexylene dimethylene                             per square          with heptane at     nonalcoholic
 terephthalate copolymer is the                        centimeter (1.5     65.6  deg.C (150    foods including
 reaction product of dimethyl                          micrograms per      deg.F) for 2        carbonated
 terephthalate or terephthalic                         square inch) of     hours:              beverages.
 acid with a mixture containing                        food-contact        terephthaloyl       Conditions of hot
 99 to 85 mole percent ethylene                        surface of the      moieties do not     fill not
 glycol and 1 to 15 mole percent                       oriented            exceed 0.09         exceeding 87.8
 of 1,4-cyclohexane-di-methanol                        copolymer when      microgram per       deg.C (190
 (70 percent trans isomer, 30                          extracted with      square centimeter   deg.F), storage
 percent cls isomer).                                  water added at      (0.60 microgram     at temperatures
                                                       87.8  deg.C (190    per square inch)    not in excess of
                                                       deg.F) and          of food-contact     48.9  deg.C (120
                                                       allowed to cool     surface.            deg.F). No
                                                       to 48.9  deg.C                          thermal treatment
                                                       (120  deg.F) in                         in the container.
                                                       contact with the
                                                       food-contact
                                                       article.
                                  ......do..........  (2) 0.23 microgram  ......do..........      Do.
                                                       per square
                                                       centimeter (1.5
                                                       micrograms per
                                                       square inch) of
                                                       food-contact
                                                       surface of
                                                       oriented
                                                       copolymer when
                                                       extracted with 3
                                                       percent (by
                                                       volume) aqueous
                                                       acetic acid added
                                                       at 87.8  deg.C
                                                       (190  deg.F) and
                                                       allowed to cool
                                                       to 48.9  deg.C
                                                       (120  deg.F) in
                                                       contact with the
                                                       food-contact
                                                       article.
                                  ......do..........  (3) 0.08 microgram  ......do..........      Do.
                                                       per square
                                                       centimeter (0.5
                                                       micro